Biomaterial Database

Postoperative autotransfusion after total knee arthroplasty. 1996

A T Berman, and R J Levenberg, and M T Tropiano, and B Parks, and S J Bosacco

Department of Orthopedic Surgery, Hahnemann University, Philadelphia, PA 19102, USA.

To evaluate the quality of shed blood postoperatively after total knee arthroplasty (TKA), the safety of autotransfusion, and to minimize homologous transfusion, the Autovac system was used for reinfusion of whole blood following cemented TKA. The system was used in 50 consecutive patients who were reinfused an average of 420 cc of whole blood. Twenty-five patients had a calcium binding resin anticoagulant within the collection canister. A second group of 25 patients had 40 cc of acid citrate dextrose anti-coagulate (ACD-A) in the collection canister as an anticoagulant. Fifteen hematologic parameters were measured during five time periods. Each study group was compared to a control group of 25 TKAs with a standard drain. The clinical safety of auto-transfusion with ACD-A was proven. Blood collected in the calcium binding resin had a statistically significant higher hemoglobin (P < .05), plasma-free hemoglobin (P < .05), fibrin split products (P < .05), and a different white blood cell differential.

UI	MeSH Term	Description	Entries
D007720	Knee Prosthesis	Replacement for a knee joint.	Knee Prostheses,Prostheses, Knee,Prosthesis, Knee
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D012116	Resins, Plant	Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)	Plant Resins
D001804	Blood Transfusion, Autologous	Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)	Autotransfusion,Autologous Blood Transfusion,Autologous Blood Transfusions,Blood Transfusions, Autologous,Transfusion, Autologous Blood,Transfusions, Autologous Blood,Autotransfusions
D002951	Citrates	Derivatives of CITRIC ACID.
D005260	Female		Females
D005947	Glucose	A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.	Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D006403	Hematologic Tests	Tests used in the analysis of the hemic system.	Blood Tests,Hematologic Test,Hematological Tests,Test, Hematologic,Tests, Hematologic,Blood Test,Hematological Test,Test, Blood,Test, Hematological,Tests, Blood,Tests, Hematological