Biomaterial Database

Effects of uneven elastic loads on breathing pattern of anesthetized and conscious men. 1977

E Agostoni, and E D'angelo, and G Torri, and L Ravenna

In anesthetized subjects rib cage strapping (RCS) did not change tidal volume (VT) and increased ventilation (V), whereas abdomen strapping (AS) markedly decreased VT and V. Both kinds of strapping decreased expiratory duration (TE), but did not change inspiratory duration (TI) and breathing rate. RCS and AS decreased lung volume by about 200 ml and increased the elastance of the repiratory system by 12 cm H2O/1 and 9 CM H20/l, repectively. The changes produced are mainly due to mechanical factors, although reflexes also seem to be operating in some cases. In conscious subjects RCS decreased VT, TI, TE and did not change V, whereas AS did not change these parameters. The different changes in conscious and anesthetized subjects show the effects of cortical influences, which also partly explain the differen effects elicited in conscious subjects by RCS and AS. The effects produced by RCS are mainly due to the sensation of hindrance to rib cage expansion, rather than to that of rib cage squeezing, as shown by experiments of RCS without reduction of rib cage volume.

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008170	Lung Compliance	The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562)	Compliance, Lung,Compliances, Lung,Lung Compliances
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D002540	Cerebral Cortex	The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulci. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.	Allocortex,Archipallium,Cortex Cerebri,Cortical Plate,Paleocortex,Periallocortex,Allocortices,Archipalliums,Cerebral Cortices,Cortex Cerebrus,Cortex, Cerebral,Cortical Plates,Paleocortices,Periallocortices,Plate, Cortical
D003243	Consciousness	Sense of awareness of self and of the environment.	Consciousnesses
D004548	Elasticity	Resistance and recovery from distortion of shape.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000005	Abdomen	That portion of the body that lies between the THORAX and the PELVIS.	Abdomens