-transparent.png){kind=logo}
Thirty patients with bronchogenic carcinoma underwent an 8 week course of induction therapy consisting of cyclophosphamide, methotrexate, vincristine, and VP 16-213 (NSC 141 540). Those who achieved objective remission or tumor stabilization were then placed on an intermittent treatment schedule with the same drugs. Of the 30 patients, 17 had an objective response, 5 were unchanged and 8 progressed. Responses were more frequent in anaplastic carcinoma (13/19) than epidermoid or adenocarcinoma (4/11). The toxicity mainly consisted of leukopenia, thrombopenia, alopecia, nausea and vomiting. The implications of these findings in the planning of further chemotherapeutic programs are discussed.
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
September 1981,
Thorax,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
June 1981,
Thorax,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
July 1976,
Cancer treatment reports,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
May 1985,
Gan no rinsho. Japan journal of cancer clinics,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
July 1981,
Cancer,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
June 1979,
Cancer treatment reviews,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
June 1982,
Cancer treatment reviews,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
January 1977,
Cancer treatment reports,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
October 1986,
Cancer biochemistry biophysics,
H J Ryssel, and
E Hasler, and
R W Sonntag, and
F Cavalli, and
J Martin, and
L Tschopp, and
K W Brunner
June 1988,
Gynecologic oncology,
