Changing pattern of portasystemic shunt surgery. 1995

J A van der Vliet, and E de Visser, and F G Buskens
Department of Surgery, St. Radboud University Hospital, Nijmegen, Netherlands.

OBJECTIVE Analysis of changes in the pattern of portasystemic shunt surgery. METHODS Single centre retrospective study. METHODS University hospital, The Netherlands. METHODS 74 patients receiving portasystemic shunts during a 15 year period, with complete follow up. METHODS Severity of disease, type of operation, early mortality, long term survival and development of encephalopathy. RESULTS The number of portasystemic shunts undertaken during the study period declined, with a rise in the proportion of emergency operations. Early mortality was 1/38 (3%) in patients with Child A disease, 2/27 (7%) in those with Child B, and 5/9 (56%) in those with Child C (p < 0.0005, chi square). Early mortality was highest (p = 0.004, Fisher's exact test) after emergency operations with 6/20 (30%), compared with 2/54 (4%) following elective shunt surgery. The 5-year cumulative survival was 77% in patients with Child A, 58% in patients with Child B, and 11% in patients with Child C disease (p < 0.001, log rank). Survival was significantly less in patients with alcoholic liver cirrhosis (p < 0.05, log rank). Postoperative encephalopathy was treated clinically in 16/73 (22%) patients, and developed irrespective of the type of decompression. CONCLUSIONS With the increasing importance of other treatments of portal hypertension and variceal haemorrhage the pattern of portasystemic shunt surgery has changed. Despite a steady decline in the number of elective decompressions, that of acute operations has been constant over the years. These procedures had a considerable early mortality. The severity of the liver disease was a strong determinant of long term survival, as was the presence of alcoholic liver cirrhosis. Postoperative encephalopathy was common and was independent of the shunt technique used. In elective cases portasystemic shunting techniques, that will not interfere with a subsequent hepatic transplantation, are preferred.

UI MeSH Term Description Entries
D006975 Hypertension, Portal Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN. Cruveilhier-Baumgarten Disease,Cruveilhier-Baumgarten Syndrome,Cruveilhier Baumgarten Disease,Cruveilhier Baumgarten Syndrome,Disease, Cruveilhier-Baumgarten,Portal Hypertension,Portal Hypertensions,Syndrome, Cruveilhier-Baumgarten
D008104 Liver Cirrhosis, Alcoholic FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING. Alcoholic Cirrhosis,Hepatic Cirrhosis, Alcoholic,Alcoholic Hepatic Cirrhosis,Alcoholic Liver Cirrhosis
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011170 Portasystemic Shunt, Surgical Surgical venous shunt between the portal and systemic circulation to effect decompression of the portal circulation. It is performed primarily in the treatment of bleeding esophageal varices resulting from portal hypertension. Types of shunt include portacaval, splenorenal, mesocaval, splenocaval, left gastric-caval (coronary-caval), portarenal, umbilicorenal, and umbilicocaval. Portosystemic Shunt, Surgical,Portasystemic Shunt,Portosystemic Shunt,Shunt, Surgical Portasystemic,Shunt, Surgical Portosystemic,Surgical Portasystemic Shunt,Surgical Portosystemic Shunt,Portasystemic Shunts,Portasystemic Shunts, Surgical,Portosystemic Shunts,Portosystemic Shunts, Surgical,Shunt, Portasystemic,Shunt, Portosystemic,Shunts, Portasystemic,Shunts, Portosystemic,Shunts, Surgical Portasystemic,Shunts, Surgical Portosystemic,Surgical Portasystemic Shunts,Surgical Portosystemic Shunts
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D001927 Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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