Biomaterial Database

Trigeminocerebellar projection to the paramedian lobule with emphasis on the climbing fibre zones: a retrograde tracing study in the rabbit. 1996

D Bukowska

Department of Neurobiology, University School of Physical Education, Poznań, Poland.

Projections of the trigeminal sensory nuclear complex (TSNC) onto the cerebellar paramedian lobule (PML) were investigated by the retrograde horseradish peroxidase (HRP) and fluorescent tracers (FB, DY) technique in the rabbit. Following injections of the tracers into the various regions of different sublobules of PML, the retrograde labelling pattern in TSNC was analyzed, especially in relation to the climbing fibre zones identified by retrograde labelling in the inferior olive (Zimny et al., 1989). The present results indicate that projections are bilateral with a clear ipsilateral preponderance. The major projections originate mainly from the dorsolateral and ventromedial regions of the principal trigeminal nucleus (Vp) except its caudal pole. Prominent input is also derived from the rostral (Vir) and caudal (Vic) pars interpolaris of the spinal trigeminal nucleus (Vsp). The cells of origin of the projections are present throughout the entire length of Vir with preference to dorsolateral and dorsal location. In Vic they tend to be distributed in the medial regions of its rostral half. Afferents form the pars oralis (Vo) of Vsp are moderate and arise mainly from the dorsomedial and dorsal regions in its caudal one-third. Projections from the pars caudalis (Vc) of Vsp and the mesencephalic trigeminal nucleus (Vmes) are absent. A topography exists in the trigeminocerebellar projections, however, no clear-cut evidence was obtained for a topical relationship between distribution of neurones in TSNC and projections sites in PML. On the other hand, certain correspondence could be found between subdivisions of TSNC and climbing fibre zones in PML. While zones C3 and C2-lateral appear to receive no trigeminal afferents, zone C1 is supplied by fibres from Vir and Vic. All subdivisions of TSNC project zones C2, D1 and D2. In sublobule f, medial (Dm) and lateral (Dl) composite zone D1 + D2 receive projections from Vic, or Vp and Vir, respectively. The present report provides new detailed data on the trigeminocerebellar system in the rabbit.

UI	MeSH Term	Description	Entries
D009434	Neural Pathways	Neural tracts connecting one part of the nervous system with another.	Neural Interconnections,Interconnection, Neural,Interconnections, Neural,Neural Interconnection,Neural Pathway,Pathway, Neural,Pathways, Neural
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D002531	Cerebellum	The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.	Cerebella,Corpus Cerebelli,Parencephalon,Cerebellums,Parencephalons
D006651	Histocytochemistry	Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.	Cytochemistry
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014276	Trigeminal Nerve	The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.	Cranial Nerve V,Fifth Cranial Nerve,Nerve V,Nervus Trigeminus,Cranial Nerve, Fifth,Fifth Cranial Nerves,Nerve V, Cranial,Nerve Vs,Nerve, Fifth Cranial,Nerve, Trigeminal,Trigeminal Nerves,Trigeminus, Nervus