[Neurobiological and psychodynamic correlations in obsessive-compulsive disorders and bulimia nervosa]. 1996

H Csef
Arbeitsbereich Psychosomatische Medizin und Psychotherapie Medizinische Poliklinik, Würzburg.

Neurobiology seems to be a great challenge for recent psychosomatic medicine. The rise of neurobiology through fascinating findings characterizes our "decade of the brain". Psychosomatic medicine tries to integrate biological, psychological and social factors of disease and health. Therefore brain research is essential for psychosomatic medicine. This paper gives a review of two psychiatric disorders which show close neurobiologic connections: bulimia nervosa (BN) and obsessive-compulsive disorder (OCD). Both disease are characterized by an increase in prevalence and have been interpreted as modern epidemic diseases. Neurobiological and psychodynamic connections will be discussed.

UI MeSH Term Description Entries
D009446 Neurobiology The study of the structure, growth, activities, and functions of NEURONS and the NERVOUS SYSTEM. Cellular Neurobiology,Molecular Neurobiology,Neurobiology, Cellular,Neurobiology, Molecular
D009771 Obsessive-Compulsive Disorder An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension. Anankastic Personality,Neurosis, Obsessive-Compulsive,Anankastic Personalities,Disorder, Obsessive-Compulsive,Disorders, Obsessive-Compulsive,Neuroses, Obsessive-Compulsive,Neurosis, Obsessive Compulsive,Obsessive Compulsive Disorder,Obsessive-Compulsive Disorders,Obsessive-Compulsive Neuroses,Obsessive-Compulsive Neurosis,Personalities, Anankastic,Personality, Anankastic
D011574 Psychoanalytic Theory Conceptual system developed by Freud and his followers in which unconscious motivations are considered to shape normal and abnormal personality development and behavior. Oral Character,Psychoanalytical Theory,Theory, Psychoanalytic,Character, Oral,Characters, Oral,Oral Characters,Psychoanalytic Theories,Psychoanalytical Theories,Theories, Psychoanalytic,Theories, Psychoanalytical,Theory, Psychoanalytical
D011602 Psychophysiologic Disorders A group of disorders characterized by physical symptoms that are affected by emotional factors and involve a single organ system, usually under AUTONOMIC NERVOUS SYSTEM control. (American Psychiatric Glossary, 1988) Psychosomatic Disorders,Psychophysiological Disorders,Psychophysiologic Disorder,Psychophysiological Disorder,Psychosomatic Disorder
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002032 Bulimia Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger". Binge Eating,Bulimias,Eating, Binge
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012701 Serotonin A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. 5-HT,5-Hydroxytryptamine,3-(2-Aminoethyl)-1H-indol-5-ol,Enteramine,Hippophaine,Hydroxytryptamine,5 Hydroxytryptamine
D015897 Comorbidity The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.

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