Separation of "uncharged" oligodeoxynucleotide analogs by anion-exchange chromatography at high pH.
1996
J G Schmidt, and
P E Nielsen, and
L E Orgel
The Salk Institute for Biological Studies, San Diego, California 92186-5800, USA.
UI
MeSH Term
Description
Entries
D009838
Oligodeoxyribonucleotides
A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties.
Separation technique in which the stationary phase consists of ion exchange resins. The resins contain loosely held small ions that easily exchange places with other small ions of like charge present in solutions washed over the resins.