-transparent.png){kind=logo}
The effects of cholesterol feeding on serum and liver cholesterol levels, fecal and biliary bile acid levels, bile acid pool size and bile acid composition were examined in 2-, 12- and 24-month-old male germ-free rats. The major bile acids in these animals were cholic and beta-muricholic acids. Cholesterol feeding increased synthesis of bile acids by 3- to 4-fold, especially that of chenodeoxycholic acid (mainly beta-muricholic acid in the rat), decreasing the cholic acid/chenodeoxycholic acid (CA/CDCA) ratio in all rats regardless of age, even though the CA/CDCA ratio increased as a linear function of age in both diet groups. Cholesterol feeding increased the serum cholesterol level markedly in aged rats. This hypercholesterolemia may be produced by the increase in CA/CDCA ratio in aged rats.
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
April 1981,
Lipids,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
November 1975,
The Journal of biological chemistry,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
May 1981,
European journal of biochemistry,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
November 2012,
Archives of pharmacal research,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
December 1977,
The American journal of clinical nutrition,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
March 1975,
Mayo Clinic proceedings,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
April 1977,
Japanese journal of pharmacology,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
October 1986,
Diabete & metabolisme,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
April 1974,
Mayo Clinic proceedings,
K Uchida, and
T Satoh, and
T Chikai, and
H Takase, and
Y Nomura, and
H Nakao, and
N Takeuchi
June 1982,
Indian journal of biochemistry & biophysics,
