BIOMAT Database Logo BIOMAT Database Logo

Influences of gender on sympathetic nerve responses to static exercise. 1996

S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Department of Radiology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033, USA.

We compared reflex responses to static handgrip at 30% maximal voluntary contraction (MVC) in 26 untrained men (mean age 35 +/- 3 yr) and 23 untrained women (mean age 39 +/- 4 yr). Women demonstrated attenuated increases in blood pressure and muscle sympathetic nerve activity (MSNA; by microneurography) compared with men. This difference was also observed during a period of posthandgrip circulatory arrest. 31P-nuclear magnetic resonance (NMR) spectroscopy studies demonstrated attenuations in the production of diprotonated phosphate and the development of cellular acidosis in women compared with men. Subjects also performed ischemic handgrip to fatigue. During this paradigm, MSNA responses were similar in the two groups, suggesting that freely perfused conditions are necessary for the full expression of the gender effect. Finally, we examined MSNA responses to adductor pollicus exercise in 7 men (26 +/- 1 yr) and 6 women (25 +/- 2 yr). MVC values and times to fatigue were similar in the two groups (MVC: men, 4.3 +/- 0.4 kg; women, 4.0 +/- 0.3 kg; not significant. Time to fatigue: men, 209 +/- 16 s; women, 287 +/- 50 s; not significant). At periods of end exercise and postexercise circulatory arrest, MSNA responses were attenuated in the women compared with the men. We conclude that, during nonischemic static exercise, sympathetic neural outflow is less in women compared with men. This response is due to an attenuated metaboreflex in women. Finally, on the basis of the adductor pollicus experiments, this effect appears independent of muscle mass, workload, and the level of training.

UI MeSH Term Description Entries
D008297 Male Males
D009119 Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D010101 Oxygen Consumption The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346) Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D005260 Female Females
D006225 Hand The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb. Hands
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000138 Acidosis A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up. Metabolic Acidosis,Acidoses,Acidoses, Metabolic,Acidosis, Metabolic,Metabolic Acidoses
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Dichloroacetate reduces sympathetic nerve responses to static exercise.
November 1991, The American journal of physiology,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Muscle sympathetic nerve responses to static leg exercise.
October 1992, Journal of applied physiology (Bethesda, Md. : 1985),
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Effects of partial neuromuscular blockade on sympathetic nerve responses to static exercise in humans.
August 1989, Circulation research,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans.
September 1985, Circulation research,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Vasomotor sympathetic nerve responses to static handgrip after simulated microgravity.
July 1999, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Responses of muscle sympathetic nerve activity to static handgrip exercise after 14 days of exposure to simulated microgravity.
July 2000, Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Determinants of skin sympathetic nerve responses to isometric exercise.
March 2006, Journal of applied physiology (Bethesda, Md. : 1985),
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Muscle sympathetic nerve responses to prolonged one-legged exercise.
April 1993, Journal of applied physiology (Bethesda, Md. : 1985),
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
Arm elevation enhances muscle sympathetic nerve activity during static exercise.
December 2000, Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University,
S M Ettinger, and D H Silber, and B G Collins, and K S Gray, and G Sutliff, and S K Whisler, and J M McClain, and M B Smith, and Q X Yang, and L I Sinoway
The effect of static exercise on renal sympathetic nerve activity in conscious cats.
March 1991, The Journal of physiology,
Copied contents to your clipboard!