BIOMAT Database Logo BIOMAT Database Logo

Molecular characterization of erythrocyte glucose-6-phosphate dehydrogenase deficiency in Al-Ain District, United Arab Emirates. 1996

R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Department of Biochemistry, Faculty of Medicine and Health Sciences, United Arab Emirates University.

In a cross-sectional study, the activity, electrophoretic mobility and genotypes of glucose-6-phosphate dehydrogenase (G6PD) were determined among healthy, UAE national school boys from Al-Ain District in the United Arab Emirates, The prevalence of G6PD deficiency in this population sample was 11%. The majority of G6PD-deficient subjects were descendants of Omani, Baluchi or Yemeni migrants. Of 18 deficient subjects, 16 had an enzyme activity of < 10% of normal while 2 had an activity of just above 10%. Electrophoresis was performed on 166 samples and showed that, apart from deficient samples, all had the normal mobility of G6PD type B. Of the 18 deficient subjects, 14 had the B type mobility of G6PD Mediterranean and 4 had the A type mobility of G6PD A-. Genotyping demonstrated that 10 had the Mediterranean mutation while 3 had the A- mutation, consistent with their electrophoretic mobility. Another 3 had the G6PD Aures mutation, recently described as polymorphic in Algeria and Spain. The mutations in the remaining 2 subjects have not yet been identified.

UI MeSH Term Description Entries
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D005955 Glucosephosphate Dehydrogenase Deficiency A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia. Deficiency of Glucose-6-Phosphate Dehydrogenase,Deficiency, GPD,Deficiency, Glucosephosphate Dehydrogenase,G6PD Deficiency,GPD Deficiency,Glucose 6 Phosphate Dehydrogenase Deficiency,Glucose-6-Phosphate Dehydrogenase Deficiency,Glucosephosphate Dehydrogenase Deficiencies,Hemolytic Anemia Due to G6PD Deficiency,Deficiencies, G6PD,Deficiencies, GPD,Deficiencies, Glucose-6-Phosphate Dehydrogenase,Deficiencies, Glucosephosphate Dehydrogenase,Deficiency of Glucose 6 Phosphate Dehydrogenase,Deficiency, G6PD,Deficiency, Glucose-6-Phosphate Dehydrogenase,Dehydrogenase Deficiencies, Glucose-6-Phosphate,Dehydrogenase Deficiencies, Glucosephosphate,Dehydrogenase Deficiency, Glucose-6-Phosphate,Dehydrogenase Deficiency, Glucosephosphate,G6PD Deficiencies,GPD Deficiencies,Glucose-6-Phosphate Dehydrogenase Deficiencies
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D014479 United Arab Emirates A federation of seven states on the southeast portion of the Arabian peninsula: Abu Dhabi, Ajman, Dubai, Fujairah, Ras al-Khaimah, Sharjah and Umm al-Qaiwain. In 1820 a treaty of peace was concluded between Great Britain and native rulers. During the 19th century the rulers agreed to suppression of the slave trade and restriction of foreign relations to Great Britain. The Trucial Council was established in 1952 and defense treaties with Great Britain terminated. In 1971 an independent six-member federation was formed, with Ras al-Khaimah joining the federation in 1972. (From Webster's New Geographical Dictionary, 1988, p1250) Abu Dhabi,Trucial States
D015995 Prevalence The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time. Period Prevalence,Point Prevalence,Period Prevalences,Point Prevalences,Prevalence, Period,Prevalence, Point,Prevalences

Related Publications

R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Neonatal screening of glucose-6-phosphate dehydrogenase deficiency in Khorfakkan, United Arab Emirates.
December 2008, Saudi medical journal,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Causes of adult female mortality in Al Ain district, United Arab Emirates.
April 1996, Journal of epidemiology and community health,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Vitamin D deficiency among healthy adolescents in Al Ain, United Arab Emirates.
January 2013, BMC public health,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Molecular characterization of erythrocyte glucose-6-phosphate dehydrogenase deficiency in Tunisia.
July 2008, Pathologie-biologie,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Aetiology of onychomycosis in Al Ain, United Arab Emirates.
January 1995, Mycoses,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Infant-feeding practices in Al-Ain, United Arab Emirates.
January 1999, Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Epidemiology of clinical hyperbilirubinaemia in Al Ain, United Arab Emirates.
June 1998, Annals of tropical paediatrics,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Secular trend in height in Al Ain-United Arab Emirates.
December 2009, Economics and human biology,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Road traffic injuries in Al-Ain City, United Arab Emirates.
December 1992, Journal of the Royal Society of Health,
R A Bayoumi, and M S Nur-E-Kamal, and M Tadayyon, and K K Mohamed, and B H Mahboob, and M M Qureshi, and M S Lakhani, and M O Awaad, and J Kaeda, and T J Vulliamy, and L Luzzatto
Seasonality and prevalence of rotavirus in Al-Ain, United Arab Emirates.
October 1994, Clinical and diagnostic virology,
Copied contents to your clipboard!