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Gramicidin S, dissolved in ethanol, penetrated into the inside of the dormant spores of Bacillus subtilis, had a partial inhibitory effect on L-alanine-initiated germination and completely inhibited their outgrowth and vegetative growth. The activity of particulate NADH oxidase of the antibiotic-treated dormant spores was also influenced significantly. Abnormal morphological changes were observed in germinated spores from gramicidin S-treated dormant spores. An immunoelectron microscopy method with colloidal gold-IgG complex showed that the penetration site of gramicidin S inside dormant spores was mainly the core region. These facts suggest that gramicidin S induces the damage of not only the outer membrane-spore coat complex but also the inner membrane surrounding the spore protoplast, and is able to penetrate into the core region of B. subtilis dormant spores.
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
March 1991,
Journal of general microbiology,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
October 1983,
Journal of bacteriology,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
August 1974,
Journal of bacteriology,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
January 2016,
Journal of bacteriology,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
February 2008,
The journal of physical chemistry. B,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
September 1976,
FEBS letters,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
May 2012,
Journal of bacteriology,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
January 2014,
PloS one,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
May 1984,
The Biochemical journal,
Y Tanimoto, and
Y Ichikawa, and
Y Yasuda, and
K Tochikubo
September 2020,
FEMS microbiology letters,
