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The results obtained with oestrogen treatment of diffuse malignant cancer of the breast are reported. Improvement was obtained in 50% of cases, 23.3% remained stationary and 26.6% worsened. Side effects were confined essentially to liver trouble of colostatic type, a disturbance that was temporary and closely linked with the drug dose employed. Some aspects of high dose antitumour hormone treatment are examined in detail: hormone dose in the induction phase and during maintenance, latency time before the appearance of the first signs of improvement, relationship between age, sexual endocrinal state and therapeutic result, correlation between time of onset of the disease, free interval and result obtained.
B Massidda, and
V Mascia, and
G Broccia, and
S Pasqualucci, and
W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
January 1949,
Bulletin of the University of Minnesota Hospitals and Minnesota Medical Foundation. University of Minnesota. Hospitals,
B Massidda, and
V Mascia, and
G Broccia, and
S Pasqualucci, and
W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
February 1954,
The American surgeon,
B Massidda, and
V Mascia, and
G Broccia, and
S Pasqualucci, and
W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
January 2002,
Clinical therapeutics,
B Massidda, and
V Mascia, and
G Broccia, and
S Pasqualucci, and
W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
April 1985,
American journal of clinical oncology,
B Massidda, and
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A Pellegrini
January 1976,
Revista clinica espanola,
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September 1988,
Drug intelligence & clinical pharmacy,
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A Desogus, and
G Luxi, and
A Pellegrini
June 1981,
Cancer nursing,
B Massidda, and
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W Deplano, and
A Desogus, and
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A Pellegrini
August 1981,
Horumon to rinsho. Clinical endocrinology,
B Massidda, and
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W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
January 1990,
International journal of fertility,
B Massidda, and
V Mascia, and
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W Deplano, and
A Desogus, and
G Luxi, and
A Pellegrini
October 1994,
JAMA,
