[Disorders of early information processing and vigilance as vulnerability markers for schizophrenia]. 1996

T Suslow, and V Arolt
Klinik für Psychiatrie der Medizinischen Universität zu Lübeck.

Disordered processes of scanning iconic memory and vigilance deficits are well-known phenomena in schizophrenics. The "Span of Apprehension" and the "Continuous Performance Test" are among the most important research techniques assessing these impairments and are considered possible neuropsychological vulnerability markers of schizophrenia. Numerous studies compared schizophrenics with psychiatric control groups on these tasks to determine the specificity of the performance deficits which represents a central criterion for vulnerability markers. The review of the empirical results suggests a non-specificity of the performance of schizophrenics on the "Span of Apprehension" and the degraded stimulus version of the Continuous Performance Test. These findings are critically discussed with reference to the technical and methodological characteristics of the studies. Furthermore, studies are presented which examined the relationship of vigilance performance on the Continuous Performance Test and rate of detecting on "Span of Apprehension" and psychopathological symptoms with the aim to evaluate the marker qualities of these research techniques for schizophrenic symptoms. According to the available data a partial symptomatic specificity can be attributed to the "Span of Apprehension".

UI MeSH Term Description Entries
D009483 Neuropsychological Tests Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D011939 Mental Recall The process whereby a representation of past experience is elicited. Recall, Mental
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001288 Attention Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating. Focus of Attention,Selective Attention,Social Attention,Attention Focus,Attention, Selective,Attention, Social,Selective Attentions
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D012559 Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. Dementia Praecox,Schizophrenic Disorders,Disorder, Schizophrenic,Disorders, Schizophrenic,Schizophrenias,Schizophrenic Disorder
D012569 Schizotypal Personality Disorder A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia. Incipient Schizophrenia,Latent Schizophrenia,Personality Disorder, Schizotypal,Pseudoneurotic Schizophrenia,Pseudopsychopathic Schizophrenia,Schizophrenia, Borderline,Schizophrenia, Latent,Schizophrenia, Pseudoneurotic,Borderline Schizophrenia,Borderline Schizophrenias,Disorder, Schizotypal Personality,Disorders, Schizotypal Personality,Incipient Schizophrenias,Latent Schizophrenias,Personality Disorders, Schizotypal,Pseudoneurotic Schizophrenias,Pseudopsychopathic Schizophrenias,Schizophrenia, Incipient,Schizophrenia, Pseudopsychopathic,Schizophrenias, Borderline,Schizophrenias, Incipient,Schizophrenias, Latent,Schizophrenias, Pseudoneurotic,Schizophrenias, Pseudopsychopathic,Schizotypal Personality Disorders

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