-transparent.png){kind=logo}
Human or bovine lactoferrin (LF) and lactoferricin (LFcin), a peptide derived from the N-terminal region of LF, each have the ability to stimulate the release of neutrophil-activating polypeptide interleukin 8 (IL-8) from human polymorphonuclear leukocytes (neutrophils, PMNs). This finding suggests that LF and LFcin may both function as immunomediators for activating the host defense system. A basic peptide, protamine, exerted the same effect as that of LF and LFcin, suggesting the importance of the basic nature of LF and LFcin in acting as an inducer of IL-8 release from PMNs.
Related Publications
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
January 1987,
Acta haematologica,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
August 1998,
Blood,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
June 1998,
Anesthesia and analgesia,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
April 1985,
Arerugi = [Allergy],
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
June 1994,
American journal of respiratory cell and molecular biology,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
January 1976,
Advances in prostaglandin and thromboxane research,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
March 1975,
Inflammation,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
May 1991,
Journal of leukocyte biology,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
August 1994,
Journal of leukocyte biology,
I Shinoda, and
M Takase, and
Y Fukuwatari, and
S Shimamura, and
M Köller, and
W König
September 2001,
Journal of leukocyte biology,
