Cobalt exposure level and variability in the hard metal industry of Japan. 1996

S Kumagai, and Y Kusaka, and S Goto
Department of Occupational Health, Osaka Prefectural Institute of Public Health, Japan.

Cobalt, used as a binder for tungsten carbide, has been demonstrated to be toxic to the lung and to be a sensitizer of the bronchial airways among hard metal workers. To determine cobalt exposure levels in 9 job groups at a hard metal factory, 935 samples were collected from 356 workers. The arithmetic means of 8-hr time-weighted averages were more than 50 micrograms/m3 (American Conference of Governmental Industrial Hygienists' threshold limit value) in the powder preparation, rubber press, and shaping groups. The within-worker and between-worker components of exposure variation were estimated for each job group using the random effects analysis-of-variance model. The geometric standard deviations indicating the within-worker and between-worker components ranged from 1.88 to 2.77 and 1.00 to 2.31, respectively.

UI MeSH Term Description Entries
D007564 Japan A country in eastern Asia, island chain between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. The capital is Tokyo. Bonin Islands
D008452 Maximum Allowable Concentration The maximum exposure to a biologically active physical or chemical agent that is allowed during an 8-hour period (a workday) in a population of workers, or during a 24-hour period in the general population, which does not appear to cause appreciable harm, whether immediate or delayed for any period, in the target population. (From Lewis Dictionary of Toxicology, 1st ed) Maximum Permissible Exposure Level,MPEL,Maximum Permissible Exposure Concentration,Allowable Concentration, Maximum,Allowable Concentrations, Maximum,Concentration, Maximum Allowable,Concentrations, Maximum Allowable,MPELs,Maximum Allowable Concentrations
D008669 Metallurgy The science, art, or technology dealing with processes involved in the separation of metals from their ores, the technique of making or compounding the alloys, the techniques of working or heat-treating metals, and the mining of metals. It includes industrial metallurgy as well as metallurgical techniques employed in the preparation and working of metals used in dentistry, with special reference to orthodontic and prosthodontic appliances. (From Jablonski, Dictionary of Dentistry, 1992, p494) Heavy Industries,Industries, Heavy,Heavy Industry,Industry, Heavy
D009790 Occupations Crafts, trades, professions, or other means of earning a living. Vocations,Occupation,Vocation
D003035 Cobalt A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. Cobalt-59,Cobalt 59
D004784 Environmental Monitoring The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment. Monitoring, Environmental,Environmental Surveillance,Surveillance, Environmental
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000395 Air Pollutants, Occupational Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. Occupational Air Pollutants,Pollutants, Occupational Air
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D016273 Occupational Exposure The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation. Exposure, Occupational,Exposures, Occupational,Occupational Exposures

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