Comparison of body composition and bone mineral measurements from two DXA instruments in young men. 1996

C M Modlesky, and R D Lewis, and K A Yetman, and B Rose, and L B Rosskopf, and T K Snow, and P B Sparling
Department of Foods and Nutrition, University of Georgia, Athens, USA.

The purpose of this study was to compare body-composition and whole-body, lumbar spine (LS), femoral neck (FN), trochanter, and Ward's triangle (WT) bone mineral measurements by using the Hologic QDR 1000W (DXAH) and the Lunar DPX-L (DXAL) dual-energy X-ray absorptiometry instruments. In addition, the ability of conversion equations to predict DXAH data from DXAL data were tested. Thirteen healthy young adult males (aged 22.2 +/- 3.6 y, 177.4 +/- 5.3 cm in height, and 72.7 +/- 9.6 kg in weight) were scanned on the same day by using DXAH and DXAL. Whereas measured body mass was not different (P > 0.05) between machines, whole-body fat mass [DXAH-DXAL (DXAdiff) = 1152 +/- 1395 g], percentage fat (DXAdiff = 1.5 +/- 1.7% of body mass), bone mineral density (BMD; DXAdiff = 0.016 +/- 0.023 g/cm2), and bone mineral content (BMC; DXAdiff = 316 +/- 50 g) were lower and whole-body fat-free soft tissue (FFST; DXAdiff = 1781 +/- 1859 g) was higher with DXAH than with DXAL. Lower fat mass (DXAdiff = 2145 +/- 855 g) and BMC (DXAdiff = 216 +/- 36 g) and higher FFST (DXAdiff = 1966 +/- 943 g) in the trunk were primarily responsible for the whole-body differences. Lower BMD and BMC values were found for LS (DXAdiff = 0.145 +/- 0.038 g/cm2 and 3 +/- 2 g, respectively), trochanter (DXAdiff = 0.100 +/- 0.044 g/cm2 and 1.7 +/- 1.0 g), and WT (DXAdiff = 0.195 +/- 0.061 g/cm2 and 1.93 +/- 0.51 g) with DXAH compared with DXAL. DXAH BMD of FN was also lower (DXAdiff = 0.141 +/- 0.032 g/cm2) than with DXAL. Only DXAH whole-body BMC and LS BMD were accurately predicted from DXAL with conversion equations. Predicted DXAH FN BMD was significantly lower than the actual DXAH value (P < or = 0.05), whereas the discrepancy between DXAH and DXAL actually increased for whole-body percentage fat and BMD (DXAdiff = 6.6 +/- 1.3% body mass and 0.020 +/- 0.025 g/cm2). In conclusion, lower whole-body fat mass, percentage fat, and BMC, and higher whole-body FFST with DXAH were due primarily to measurement differences in the trunk. Whereas conversion equations accurately predicted DXAH whole-body BMC and LS BMD from DXAL measurements in young adult males, they did not accurately predict DXAH, percentage fat, and BMD of the whole body and FN BMD.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D008903 Minerals Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Mineral
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D001823 Body Composition The relative amounts of various components in the body, such as percentage of body fat. Body Compositions,Composition, Body,Compositions, Body
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D005260 Female Females
D005272 Femur Neck The constricted portion of the thigh bone between the femur head and the trochanters. Femoral Neck,Neck, Femoral,Neck, Femur
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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