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Removal of external Ca2+ facilitated endogenous taurine release in cultured rat astrocytes. The stimulated release was not affected by furosemide, sucrose, tetrodotoxin and 3,4-dichlorobenzamil, but partially inhibited by nifedipine. Omission of external Na+ increased basal taurine release, and the effects of Na+ removal and Ca2+ depletion on the release were additive. The Na(+)-free condition did not affect Ca2+ paradox-induced cell death in astrocytes. These findings suggest that Ca2+ depletion facilitates taurine release in a mechanism independent of volume and the Na+ gradient and that the release is not involved in Ca2+ paradox-induced delayed cell toxicity in astrocytes.
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
May 1994,
Journal of neuroscience research,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
October 2005,
Neurochemistry international,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
October 1994,
Brain research,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
June 1999,
Biochemical and biophysical research communications,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
November 2003,
Glia,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
January 1990,
Glia,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
June 1991,
Neuroscience letters,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
January 2002,
Brain research,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
January 2005,
Glia,
K Takuma, and
T Matsuda, and
Y Kishida, and
S Asano, and
J Azuma, and
A Baba
January 1989,
Neuroscience,
