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One hundred and twenty-two patients have been studied in order to evaluate the usefulness of the amylase creatinine clearance ratio (ACCR) as a simple diagnostic test for acute pancreatitis. Sixteen out of 17 patients with acute pancreatitis had significant elevations in ACCR; in only 10 of these 17 cases was the serum amylase greater than 1200iu/l. The mean ACCR was within the normal range in control patients, in patients with chronic gastro-intestinal disease and in patients with acute abdominal conditions excluding pancreatitis; however, the mean serum amylase was significantly greater in patients with acute abdominal conditions than in the control group (P less than 0-05). The ACCR remained significantly elevated in patients with acute pancreatitis for longer than either serum or urine amylase values. The findings of the study suggest that the amylase creatinine clearance ratio is a simple yet reliable diagnostic test which could be used when screening patients suspected of having acute pancreatitis.
W R Murray, and
C Mackay
March 1977,
The New England journal of medicine,
W R Murray, and
C Mackay
December 1977,
Gastroenterology,
W R Murray, and
C Mackay
December 1977,
Hawaii medical journal,
W R Murray, and
C Mackay
June 1978,
Archives of internal medicine,
W R Murray, and
C Mackay
April 1975,
The New England journal of medicine,
W R Murray, and
C Mackay
January 1979,
Digestion,
W R Murray, and
C Mackay
May 1981,
Schweizerische medizinische Wochenschrift,
W R Murray, and
C Mackay
January 1979,
Acta chirurgica Belgica,
W R Murray, and
C Mackay
January 1977,
Digestion,
W R Murray, and
C Mackay
July 1981,
Bulletin of the Osaka Medical School,
