Biomaterial Database

Pharmacokinetic study and clinical evaluation of cefpodoxime proxetil in the elderly with impaired renal function. 1995

T Ishioka

Edogawa Hospital, Takasago Branch, Katsushika-ku, Tokyo, Japan.

UI	MeSH Term	Description	Entries
D007674	Kidney Diseases	Pathological processes of the KIDNEY or its component tissues.	Disease, Kidney,Diseases, Kidney,Kidney Disease
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011355	Prodrugs	A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.	Drug Precursor,Drug Precursors,Pro-Drug,Prodrug,Pro-Drugs,Precursor, Drug,Precursors, Drug,Pro Drug,Pro Drugs
D002511	Cephalosporins	A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.	Antibiotics, Cephalosporin,Cephalosporanic Acid,Cephalosporin,Cephalosporin Antibiotic,Cephalosporanic Acids,Acid, Cephalosporanic,Acids, Cephalosporanic,Antibiotic, Cephalosporin,Cephalosporin Antibiotics
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000097627	Cefpodoxime Proxetil	A prodrug of its active metabolite CEFPODOXIME.	1-(Isopropoxycarbonyloxy)ethyl-7-(2-(2-Amino-4-thiazolyl)-2-(Methoxyimino)Acetamido)-3-Methoxymethyl-8-oxo-5-thia-1-Azabicyclo(4,2,0)-oct-2-ene-2-Carboxylate,Cephalosporin 807,Orelox,Otreon,U-76252,CS 807,CS-807,U 76252,Vantin,76252, U,807, CS,807, Cephalosporin,Proxetil, Cefpodoxime,U76252
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D000369	Aged, 80 and over	Persons 80 years of age and older.	Oldest Old
D015296	Ceftizoxime	A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.	Ceftizoxime Sodium,Cefizox,Ceftizoxime Monosodium Salt,FK-749,FK749,FR-13749,SK&F 88373-2,SKF-88373,FK 749,FR 13749,FR13749,Monosodium Salt, Ceftizoxime,SK&F 88373 2,SK&F 883732,SKF 88373,SKF88373,Salt, Ceftizoxime Monosodium,Sodium, Ceftizoxime