Biomaterial Database

Mass spectrometric study of 5,6- and 5,7-dihydroxytryptamines and their biological precursors. 1996

A Bertazzo, and S Catinella, and P Traldi

Department of Pharmaceutical Sciences, University of Padova, Italy.

UI	MeSH Term	Description	Entries
D007536	Isomerism	The phenomenon whereby certain chemical compounds have structures that are different although the compounds possess the same elemental composition. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)	Isomerisms
D012701	Serotonin	A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.	5-HT,5-Hydroxytryptamine,3-(2-Aminoethyl)-1H-indol-5-ol,Enteramine,Hippophaine,Hydroxytryptamine,5 Hydroxytryptamine
D015115	5,6-Dihydroxytryptamine	Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research.	3-(2-Aminoethyl)indole-5,6-diol,5,6 Dihydroxytryptamine
D015116	5,7-Dihydroxytryptamine	Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool.	3-(2-Aminoethyl)-1H-indole-5,7-diol,5,7-Dihydroxytryptamine Creatine Sulfate,5,7 Dihydroxytryptamine,5,7 Dihydroxytryptamine Creatine Sulfate,Creatine Sulfate, 5,7-Dihydroxytryptamine,Sulfate, 5,7-Dihydroxytryptamine Creatine
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular
D016339	Spectrometry, Mass, Fast Atom Bombardment	A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.	Fast Atom Bombardment Mass Spectrometry,Fast Atom Bombardment Mass Spectroscopy,Mass Spectrometry, Fast Atom Bombardment,Mass Spectroscopy, Fast Atom Bombardment,Spectroscopy, Mass, Fast Atom Bombardment
D018629	Spectrometry, Mass, Secondary Ion	A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.	Mass Spectrometry, Secondary Ion,Mass Spectroscopy, Secondary Ion,SIMS Microscopy,Secondary Ion Mass Spectrometry,Secondary Ion Mass Spectrometry Microscopy,Spectroscopy, Mass, Secondary Ion,Secondary Ion Mass Spectroscopy,Secondary Ion Mass Spectroscopy Microscopy