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A 3-year prospective study of the clinical performance of daily disposable contact lenses compared with frequent replacement and conventional daily wear contact lenses. 1996

O D Solomon, and M I Freeman, and E L Boshnick, and W M Cannon, and B W Dubow, and R T Kame, and J C Lanier, and R W Lopanik, and T G Quinn, and L E Rigel, and D D Sherrill, and M J Stiegmeier, and R S Teiche, and L G Zigler, and G W Mertz, and R J Nason
Solomon, Scholiton, Marcotty, & Roth, MD's Inc., Beachwood, OH, USA.

OBJECTIVE To determine the clinical performance of daily disposable contact lens wear compared to conventional daily wear contact lenses and frequent replacement contact lenses. METHODS This 3-year prospective study was conducted in 12 U.S. practices. Of 338 eligible subjects enrolled (126 conventional daily wear, 144 frequent replacement, and 68 daily disposable), 229 subjects disposable group were compared with the conventional daily wear group and two sub-groups of frequent replacement subjects: (a) those with replacement at 2-weak intervals and (b) those with replacement at 1 or 3 months. RESULTS Comparing the daily disposable and conventional daily wear groups, the daily disposable subjects were more likely to be asymptomatic, reported fewer symptoms of redness, cloudy vision and grittiness/dirty sensation, reported better vision and overall satisfaction, and had fewer lens surface deposits, complications, tarsal abnormalities, and unscheduled visits, while conventional daily wear subjects reported better lens handling. Comparing the daily disposable and frequent replacement (1/3 months) groups, daily disposable subjects reported fewer symptoms of foreign body sensation, redness, cloudy vision and grittiness/dirty sensation, reported better subjective vision, comfort and overall satisfaction, and has fewer lens surface deposits, complications, and tarsal abnormalities, while frequent replacement (1/3 months) subjects reported fewer dryness symptoms and better lens handling. Comparing the daily disposable and frequent replacement (2-weeks) groups, daily disposable subjects reported better subjective vision and overall satisfaction and had fewer lens surface deposits and tarsal abnormalities, while frequent replacement (2-weeks) subjects reported fewer photophobia symptoms. CONCLUSIONS The results indicate that daily disposable wear may be the most trouble-free way of wearing contact lenses.

UI MeSH Term Description Entries
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D003261 Contact Lenses Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999) Lenses, Contact,Contact Lens,Lens, Contact
D004209 Disposable Equipment Apparatus, devices, or supplies intended for one-time or temporary use. Equipment, Disposable
D005128 Eye Diseases Diseases affecting the eye. Eye Disorders,Eye Disease,Eye Disorder
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014785 Vision, Ocular The process in which light signals are transformed by the PHOTORECEPTOR CELLS into electrical signals which can then be transmitted to the brain. Vision,Light Signal Transduction, Visual,Ocular Vision,Visual Light Signal Transduction,Visual Phototransduction,Visual Transduction,Phototransduction, Visual,Transduction, Visual
D014786 Vision Disorders Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peripheral vision. These may result from EYE DISEASES; OPTIC NERVE DISEASES; VISUAL PATHWAY diseases; OCCIPITAL LOBE diseases; OCULAR MOTILITY DISORDERS; and other conditions (From Newell, Ophthalmology: Principles and Concepts, 7th ed, p132). Hemeralopia,Macropsia,Micropsia,Day Blindness,Metamorphopsia,Vision Disability,Visual Disorders,Visual Impairment,Blindness, Day,Disabilities, Vision,Disability, Vision,Disorder, Visual,Disorders, Visual,Hemeralopias,Impairment, Visual,Impairments, Visual,Macropsias,Metamorphopsias,Micropsias,Vision Disabilities,Vision Disorder,Visual Disorder,Visual Impairments
D014792 Visual Acuity Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast. Acuities, Visual,Acuity, Visual,Visual Acuities

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