Prevalence of iodine deficiency disorders and goitre in Chad. 1996

K Wyss, and C Guiral, and A Ndikuyeze, and G Malonga, and M Tanner
Bureau Appui Santé Environnement, N'Djamena, Chad.

A nationwide sample survey was conducted in Chad to establish the prevalence of iodine deficiency disorders (IDD). The country was stratified into the Sahel zone and the Sudan zone, the latter including the city of N'Djamena. The analysis followed a stratification whereby the city of N'Djamena was also separately analysed. A total of 1171 people between 10 and 20 years of age were included in the survey. The overall weighted prevalence of goitre, evaluated by a clinical examination, was 63%. In the Sudan zone the prevalence was 70%, in the Sahel zone 64% and for the capital, N'Djamena, 25%. There were significant differences in the frequency of goitre between the three zones. Females-as established in surveys from other areas and countries-had goitre significantly more often. The prevalence of cretinism varied between 0 and 1.2%, and was highest in the Sahel zone. Amongst the sampled population of the Sudan zone, 33% had less than 20 micrograms/l of urinary iodine, indicating severe iodine deficiency. In the Sahel zone and in N'Djamena the figures reached 8 and 1%. There were high levels of thiocyanate anions in urine reaching medians between 21 and 27 mg/l in the geographical stratas. This probably decreases the bio-availability of iodine. These data show that there is a high endemicity of goitre in Chad and provide a basis for interventions as part of a national action plan against IDD, which will be adapted to the social, cultural and economic situation of the country and to available health services.

UI MeSH Term Description Entries
D007455 Iodine A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. Iodine-127,Iodine 127
D008297 Male Males
D002596 Chad A republic in central Africa, east of NIGER, west of SUDAN and south of LIBYA. Its capital is N'Djamena.
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003409 Congenital Hypothyroidism A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA. Cretinism,Myxedema, Congenital,Endemic Cretinism,Fetal Iodine Deficiency Disorder,Cretinism, Endemic,Hypothyroidism, Congenital
D004812 Epidemiologic Methods Research techniques that focus on study designs and data gathering methods in human and animal populations. Epidemiologic Method,Epidemiological Methods,Methods, Epidemiologic,Epidemiological Method,Method, Epidemiologic,Method, Epidemiological,Methods, Epidemiological
D005260 Female Females
D006042 Goiter Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC). Goiters
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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