We reviewed the records of all patients with carpal tunnel syndrome who underwent carpal tunnel release by the same neurosurgeon between 1980 and 1990. Of the total 102 patients, 71 patients (70%) had bilateral symptoms. Twenty-six patients in this group (37%) underwent bilateral surgery first on the more severely affected hand, and 1 month later on the contralateral hand. The remaining 45 patients with bilateral symptoms had surgery only on the more severely affected hand, contralateral surgery being withheld for various reasons. These 45 patients were sent follow-up questionnaires to evaluate the symptoms on the hand not treated surgically. The minimum follow up time after surgery was 14 months with an overall mean follow up of 5 years. Of the 33 respondents to the questionnaire, 15 patients stated that symptoms had disappeared in the non-operated hand, 4 said that their symptoms had improved, and 11 reported that symptoms had stayed the same. Three patients eventually underwent surgery on this previously non-operated hand. Thus, 58% of those who responded stated that; without surgery, the symptoms on their contralateral hand either improved or disappeared after surgery on the other hand. We suggest that simultaneous bilateral carpal tunnel surgery may be unnecessary for some patients with bilateral symptoms.