Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?
1996
G S Firestein
Division of Rheumatology, University of California at San Diego School of Medicine, La Jolla 92093, USA.
UI
MeSH Term
Description
Entries
D005347
Fibroblasts
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
Fibroblast
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001172
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
Rheumatoid Arthritis
D013583
Synovial Membrane
The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.