The author induced experimental lung embolia by venous administration of liquid fat or licopodium spores in 26 rabbits. Materials, obtained from myocardium of the experimental animals, were examined histologicaly and histochemicaly. The method of Lie et al. (1971) was used for establishing early ischemic changes in myofibers. The author recommended licopodium embolia as a good model for examining changes in myocardium after lung embolia. She indicated development of shock phenomena in animals with lung embolia, presenting signs of coronary insufficiency, including formation of sites of ischemic myofibers. With these changes the author explained the serious difficulties at the clinic in diagnosing and differentiating lung embolia from myocardial infarction even after electrocardiographic control.