Synthesis and properties of Praziquantel, a novel broad spectrum anthelmintic with excellent activity against Schistosomes and Cestodes. 1977

J Seubert, and R Pohlke, and F Loebich

Synthesis and properties of 2-cyclohexylcarbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazino [2,1-a] isoquinolin-4-one, a novel anthelmintic with excellent activity against all species of Schistosomes pathogenic to man and a wide range of cestodes, will be reported.

UI MeSH Term Description Entries
D007546 Isoquinolines A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
D000923 Anticestodal Agents Agents used to treat tapeworm infestations in man or animals. Taeniacides,Scolicidal Agents,Scolicides,Agents, Anticestodal,Agents, Scolicidal
D012556 Schistosomicides Agents that act systemically to kill adult schistosomes. Antischistosomal Agent,Antischistosomal Agents,Schistosomicide,Agent, Antischistosomal,Agents, Antischistosomal

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