Respiratory training, hypoxic ventilatory response and acute mountain sickness. 1996

G Markov, and R Orler, and U Boutellier
Swiss Federal Institute of Technology, Zürich, Switzerland.

A low hypoxic ventilatory response (HVR) has been observed in endurance athletes and has also been associated with low exercise ventilation and a high susceptibility to acute mountain sickness (AMS). In other studies, respiratory training was found to improve cycling endurance and decrease exercise ventilation. We therefore hypothesized that respiratory training alone may reduce HVR and increase AMS susceptibility. In 16 healthy subjects, we measured HVR (delta VE vs. delta SaO2) and the susceptibility to AMS (Lake Louise Score). Eight subjects then underwent respiratory training (30 min isocapnic hyperpnea, 4-5 times weekly, 4-5 weeks), thereby increasing breathing endurance (the time to exhaustion while breathing at 60-75% of MVV) from 455 +/- 193 sec to 2049 +/- 476 sec (p < 0.05). Eight subjects served as controls. No significant change of HVR (0.67 +/- 0.36 vs. 0.55 +/- 0.22) or of AMS score (3.5 +/- 2.1 vs. 3.9 +/- 2.2) was observed after training, and there was no significant difference from controls. We conclude that respiratory training neither depresses HVR nor increases the risk of AMS.

UI MeSH Term Description Entries
D008297 Male Males
D010806 Physical Education and Training Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY. Education, Physical,Physical Education,Physical Education, Training
D010807 Physical Endurance The time span between the beginning of physical activity by an individual and the termination because of exhaustion. Endurance, Physical,Physical Stamina,Stamina, Physical
D012132 Respiratory Muscles These include the muscles of the DIAPHRAGM and the INTERCOSTAL MUSCLES. Ventilatory Muscles,Respiratory Muscle,Muscle, Respiratory,Muscle, Ventilatory,Muscles, Respiratory,Muscles, Ventilatory,Ventilatory Muscle
D005080 Exercise Test Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. Arm Ergometry Test,Bicycle Ergometry Test,Cardiopulmonary Exercise Testing,Exercise Testing,Step Test,Stress Test,Treadmill Test,Cardiopulmonary Exercise Test,EuroFit Tests,Eurofit Test Battery,European Fitness Testing Battery,Fitness Testing,Physical Fitness Testing,Arm Ergometry Tests,Bicycle Ergometry Tests,Cardiopulmonary Exercise Tests,Ergometry Test, Arm,Ergometry Test, Bicycle,Ergometry Tests, Arm,Ergometry Tests, Bicycle,EuroFit Test,Eurofit Test Batteries,Exercise Test, Cardiopulmonary,Exercise Testing, Cardiopulmonary,Exercise Tests,Exercise Tests, Cardiopulmonary,Fitness Testing, Physical,Fitness Testings,Step Tests,Stress Tests,Test Battery, Eurofit,Test, Arm Ergometry,Test, Bicycle Ergometry,Test, Cardiopulmonary Exercise,Test, EuroFit,Test, Exercise,Test, Step,Test, Stress,Test, Treadmill,Testing, Cardiopulmonary Exercise,Testing, Exercise,Testing, Fitness,Testing, Physical Fitness,Tests, Arm Ergometry,Tests, Bicycle Ergometry,Tests, Cardiopulmonary Exercise,Tests, EuroFit,Tests, Exercise,Tests, Step,Tests, Stress,Tests, Treadmill,Treadmill Tests
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000532 Altitude Sickness Multiple symptoms associated with reduced oxygen at high ALTITUDE. Mountain Sickness,Altitude Hypoxia,Altitude Hypoxias,Hypoxia, Altitude,Sickness, Altitude,Sickness, Mountain
D000860 Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies

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