Formation of bis(hydroxyalkyl)-N-nitrosamines as products of the nitrosation of spermidine.
1977
J H Hotchkiss, and
R A Scanlan, and
L M Libbey
UI
MeSH Term
Description
Entries
D009602
Nitrosamines
A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.
Nitrosamine
D006900
Hydroxylation
Placing of a hydroxyl group on a compound in a position where one did not exist before. (Stedman, 26th ed)
Hydroxylations
D000478
Alkylation
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
Alkylations
D013095
Spermidine
A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.