Biomaterial Database

Molecular identification of astroglial neutral amino acid transport systems. 1996

S Bröer

Physiologisch-chemisches Institut, Universität, Tübingen, Deutschland.

Astrocytes, like other mammalian cells, possess several different amino acid transport systems with overlapping substrate specificity. They are involved in nutrition of the astrocyte itself and the metabolic traffic between astrocytes and neurons. Recent advances in molecular cloning techniques led to the identification of several amino acid transport proteins, which are in part present in astrocytes as well.

UI	MeSH Term	Description	Entries
D002352	Carrier Proteins	Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes.	Binding Proteins,Carrier Protein,Transport Protein,Transport Proteins,Binding Protein,Protein, Carrier,Proteins, Carrier
D003001	Cloning, Molecular	The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.	Molecular Cloning
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001253	Astrocytes	A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.	Astroglia,Astroglia Cells,Astroglial Cells,Astrocyte,Astroglia Cell,Astroglial Cell,Astroglias,Cell, Astroglia,Cell, Astroglial
D026905	Amino Acid Transport Systems	Cellular proteins and protein complexes that transport amino acids across biological membranes.	Amino Acid Permeases,Amino Acid Transporters,Amino Acid Permease,Amino Acid Transporter,Permease, Amino Acid,Permeases, Amino Acid,Transporters, Amino Acid