Biomaterial Database

Increased bleeding time after magnesium sulfate infusion. 1996

M Kynczl-Leisure, and L A Cibils

University of Chicago and the Chicago Lying-in Hospital, IL 60637, USA.

Personal observation suggested that blood loss increased among patients with preeclampsia who received magnesium sulfate infusions. Bleeding time (modified Ivy) was checked before infusion of magnesium and at the completion of infusion for nine patients with preeclampsia and three who did not receive magnesium. Bleeding time more than doubled among patients who needed magnesium and did not change among controls.

UI	MeSH Term	Description	Entries
D008278	Magnesium Sulfate	A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)	Magnesium Sulfate, Heptahydrate,Heptahydrate Magnesium Sulfate,Sulfate, Magnesium
D011225	Pre-Eclampsia	A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.	Toxemias, Pregnancy,EPH Complex,EPH Gestosis,EPH Toxemias,Edema-Proteinuria-Hypertension Gestosis,Gestosis, EPH,Hypertension-Edema-Proteinuria Gestosis,Preeclampsia,Preeclampsia Eclampsia 1,Pregnancy Toxemias,Proteinuria-Edema-Hypertension Gestosis,Toxemia Of Pregnancy,1, Preeclampsia Eclampsia,1s, Preeclampsia Eclampsia,EPH Toxemia,Eclampsia 1, Preeclampsia,Eclampsia 1s, Preeclampsia,Edema Proteinuria Hypertension Gestosis,Gestosis, Edema-Proteinuria-Hypertension,Gestosis, Hypertension-Edema-Proteinuria,Gestosis, Proteinuria-Edema-Hypertension,Hypertension Edema Proteinuria Gestosis,Of Pregnancies, Toxemia,Of Pregnancy, Toxemia,Pre Eclampsia,Preeclampsia Eclampsia 1s,Pregnancies, Toxemia Of,Pregnancy Toxemia,Pregnancy, Toxemia Of,Proteinuria Edema Hypertension Gestosis,Toxemia Of Pregnancies,Toxemia, EPH,Toxemia, Pregnancy,Toxemias, EPH
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D001760	Bleeding Time	Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.	Aspirin Tolerance Test,Bleeding Time, Template,Duke Method,Ivy Method,Template Bleeding Time,Aspirin Tolerance Tests,Bleeding Times,Bleeding Times, Template,Method, Duke,Method, Ivy,Template Bleeding Times,Test, Aspirin Tolerance,Tests, Aspirin Tolerance,Time, Bleeding,Time, Template Bleeding,Times, Bleeding,Times, Template Bleeding,Tolerance Test, Aspirin,Tolerance Tests, Aspirin
D005260	Female		Females
D006487	Hemostasis	The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.	Hemostases
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M Kynczl-Leisure, and L A Cibils

The effect of magnesium sulfate on bleeding time in pregnancy.

October 1995, American journal of obstetrics and gynecology,

M Kynczl-Leisure, and L A Cibils

Bleeding time prolongation after dextran infusion.

January 1958, Bibliotheca haematologica,

M Kynczl-Leisure, and L A Cibils

Hyperphosphatemia during magnesium sulfate infusion.

September 1994, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,

M Kynczl-Leisure, and L A Cibils

Continuous intravenous infusion of magnesium sulfate after acute myocardial infarction.

January 1990, Magnesium and trace elements,

M Kynczl-Leisure, and L A Cibils

Effect of magnesium infusion on bleeding time in healthy male volunteers.

October 1999, Scandinavian journal of clinical and laboratory investigation,

M Kynczl-Leisure, and L A Cibils

Urinary magnesium, calcium, and phosphate excretion during magnesium sulfate infusion.

October 1981, Obstetrics and gynecology,

M Kynczl-Leisure, and L A Cibils

The effect of magnesium sulfate on bleeding time and nitric oxide production in preeclamsia.

January 2011, Pakistan journal of biological sciences : PJBS,