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BACKGROUND As more children survive childhood cancers, the population at risk for second malignant tumors increases. The development of melanoma as a second malignant tumor is not well described. METHODS The M.D. Anderson Cancer Center's 50-year experience with patients who developed melanoma after treatment of a childhood cancer was retrospectively reviewed. RESULTS One hundred seventy-two patients with a second malignancy were identified; 11 patients had melanoma as a second malignancy. The most common first malignancies were Hodgkin's disease, brain tumors, and retinoblastomas. Melanoma developed in an irradiated field in 4 patients. Six patients had lymphatic or distant metastasis at diagnosis. Five of 11 patients died of melanoma. CONCLUSIONS Factors contributing to melanoma as a second malignancy may include genetic factors and the effects of chemotherapy and radiation. Survivors of childhood malignancy should be considered at risk for developing melanoma, and suspicious pigmented lesions should be carefully evaluated.
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
May 2012,
Pediatric blood & cancer,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
May 2012,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
March 1989,
British journal of cancer,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
May 2024,
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
December 2023,
JACC. CardioOncology,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
December 2002,
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
January 1989,
Radiologic technology,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
January 2004,
Pathology oncology research : POR,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
August 1994,
Ugeskrift for laeger,
C A Corpron, and
C T Black, and
M I Ross, and
C S Herzog, and
H L Ried, and
K P Lally, and
R J Andrassy
March 2010,
Archives of dermatology,
