BIOMAT Database Logo BIOMAT Database Logo

The permissive role of hyperthermia in the disaggregation of brain polysomes by L-dopa or D-amphetamine. 1977

M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman

UI MeSH Term Description Entries
D007980 Levodopa The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. L-Dopa,3-Hydroxy-L-tyrosine,Dopaflex,Dopar,L-3,4-Dihydroxyphenylalanine,Larodopa,Levopa,3 Hydroxy L tyrosine,L 3,4 Dihydroxyphenylalanine,L Dopa
D008297 Male Males
D011132 Polyribosomes A multiribosomal structure representing a linear array of RIBOSOMES held together by messenger RNA; (RNA, MESSENGER); They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) Polysomes,Polyribosome,Polysome
D001831 Body Temperature The measure of the level of heat of a human or animal. Organ Temperature,Body Temperatures,Organ Temperatures,Temperature, Body,Temperature, Organ,Temperatures, Body,Temperatures, Organ
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D003913 Dextroamphetamine The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic. d-Amphetamine,Curban,Dexamfetamine,Dexamphetamine,Dexedrine,Dextro-Amphetamine Sulfate,DextroStat,Dextroamphetamine Sulfate,Oxydess,d-Amphetamine Sulfate,dextro-Amphetamine,Dextro Amphetamine Sulfate,Sulfate, Dextroamphetamine,d Amphetamine,d Amphetamine Sulfate,dextro Amphetamine
D005334 Fever An abnormal elevation of body temperature, usually as a result of a pathologic process. Pyrexia,Fevers,Pyrexias
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013696 Temperature The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms. Temperatures
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
L-dopa: disaggregation of brain polysomes and elevation of brain tryptophan.
August 1971, Science (New York, N.Y.),
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Hyperthermia and disaggregation of brain polysomes induced by bacterial pyrogen.
July 1979, Life sciences,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Participation of dopamine- and serotonin- receptors in the disaggregation of brain polysomes by L-dopa and L-5-HTP.
June 1975, Journal of neurochemistry,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Translation of mRNA associated with monosomes and residual polysomes following disaggregation of brain polysomes by LSD and hyperthermia.
April 1982, Neurochemical research,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Disaggregation of brain polysomes after LSD in vivo. Involvement of LSD-induced hyperthermia.
December 1979, Neurochemical research,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Disaggregation of brain polysomes induced by electroconvulsive treatment.
February 1968, Journal of neurochemistry,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Dopamine: mediator of brain polysome disaggregation after L-dopa.
August 1972, Science (New York, N.Y.),
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Analysis of the aggressiveness-stereotypy complex induced in mice by amphetamine or D,L-dopa. II.
January 1974, Polish journal of pharmacology and pharmacy,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
D-amphetamine disaggregates brain polysomes via a dopaminergic mechanism.
March 1975, Proceedings of the National Academy of Sciences of the United States of America,
M A Moskowitz, and D Rubin, and J Liebschutz, and H N Munro, and T S Nowak, and R J Wurtman
Ultrastructural evidence against in vivo disaggregation of brain polyribosomes after administration of L-dopa or phenylalanine.
January 1973, Journal of neural transmission,
Copied contents to your clipboard!