BIOMAT Database Logo BIOMAT Database Logo

Micromanipulation improves in-vitro fertilization results after epididymal or testicular sperm aspiration in patients with congenital absence of the vas deferens. 1996

I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Department of Urology, Chaim Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Israel.

In all, 58 couples suffering from infertility because of congenital bilateral absence of the vas deferens underwent a total of 67 combined microsurgical epididymal aspiration or testicular sperm extraction (TESE) and in-vitro fertilization (IVF) treatments. The oocytes recovered were inseminated by either the microdroplet IVF technique (N = 20), subzonal insemination (SUZI; n = 10) or intracytoplasmic sperm injection (ICSI; n = 37). Of the ICSI cycles, 12 were performed using spermatozoa obtained by TESE. Fertilization rates for epididymal spermatozoa were significantly higher for SUZI (17.9%, 17/95) and ICSI (34.4%), 137/398) than for microdroplet IVF (5.2%, 18/343) cycles. The proportion of cycles in which fertilization was achieved was higher in the SUZI (80%) and ICSI (95%) cycles than in the IVF cycles (45%). Delivery or an ongoing pregnancy was achieved in one (5%) IVF cycle, two (20%) SUZI cycles and seven (18.95) ICSI cycles. SUZI or ICSI using epididymal or testicular spermatozoa significantly improved the oocyte fertility rate. The ICSI procedure was especially advantageous in patients for whom spermatozoa were obtained from a testicular biopsy.

UI MeSH Term Description Entries
D007248 Infertility, Male The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility. Sterility, Male,Sub-Fertility, Male,Subfertility, Male,Male Infertility,Male Sterility,Male Sub-Fertility,Male Subfertility,Sub Fertility, Male
D008297 Male Males
D008845 Microinjections The injection of very small amounts of fluid, often with the aid of a microscope and microsyringes. Microinjection
D008846 Micromanipulation The performance of dissections, injections, surgery, etc., by the use of micromanipulators (attachments to a microscope) that manipulate tiny instruments. Micromanipulations
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D003593 Cytoplasm The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990) Protoplasm,Cytoplasms,Protoplasms
D004822 Epididymis The convoluted cordlike structure attached to the posterior of the TESTIS. Epididymis consists of the head (caput), the body (corpus), and the tail (cauda). A network of ducts leaving the testis joins into a common epididymal tubule proper which provides the transport, storage, and maturation of SPERMATOZOA.
D005260 Female Females
D005306 Fertilization The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE. Conception,Fertilization, Delayed,Fertilization, Polyspermic,Conceptions,Delayed Fertilization,Delayed Fertilizations,Fertilizations,Fertilizations, Delayed,Fertilizations, Polyspermic,Polyspermic Fertilization,Polyspermic Fertilizations
D005307 Fertilization in Vitro An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro. Test-Tube Fertilization,Fertilizations in Vitro,In Vitro Fertilization,Test-Tube Babies,Babies, Test-Tube,Baby, Test-Tube,Fertilization, Test-Tube,Fertilizations, Test-Tube,In Vitro Fertilizations,Test Tube Babies,Test Tube Fertilization,Test-Tube Baby,Test-Tube Fertilizations

Related Publications

I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Quantitative evaluation of spermatogenesis by testicular histology in men with congenital absence of the vas deferens undergoing epididymal sperm aspiration.
January 1990, Human reproduction (Oxford, England),
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Relationship of epididymal sperm antibodies to their in vitro fertilization capacity in men with congenital absence of the vas deferens.
November 1992, Fertility and sterility,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Two births after microsurgical sperm aspiration in congenital absence of vas deferens.
December 1988, Lancet (London, England),
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Pregnancy following in vitro fertilization and embryo transfer by microsurgical epididymal sperm aspiration from a patient with congenital absence of the vas deferens: a case report.
February 1996, Zhonghua yi xue za zhi = Chinese medical journal; Free China ed,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Cystic fibrosis mutations impair the fertilization rate of epididymal sperm from men with congenital absence of the vas deferens.
August 1993, Human reproduction (Oxford, England),
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Epididymal Appearance in Congenital Absence of Vas Deferens.
June 2021, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Congenital absence of the vas deferens. The fertilizing capacity of human epididymal sperm.
December 1990, The New England journal of medicine,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Cystic fibrosis gene mutations do not affect sperm function during in vitro fertilization with micromanipulation for men with bilateral congenital absence of vas deferens.
August 1995, Fertility and sterility,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Percutaneous epididymal sperm aspiration in a man with congenital bilateral absence of the vas deferens undergoing an assisted reproduction program.
June 2000, Singapore medical journal,
I Madgar, and D S Seidman, and D Levran, and M Yonish, and A Augarten, and Z Yemini, and S Mashiach, and J Dor
Correlation between epididymal length and fertilization rate in men with congenital absence of the vas deferens.
February 1994, Fertility and sterility,
Copied contents to your clipboard!