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Lymphocytes and monocytes express various levels of membrane-bound CD23, the low affinity receptor for IgE (Fc epsilon RII), and in some cases release it as a soluble form. Soluble CD23 (sCD23) has been implicated in the regulation of many immunological functions of T and B lymphocytes, macrophages and myeloid cells in humans. To study serum sCD23 levels in inflammatory conditions, we selected a systemic disease sensitive to corticotherapy, the giant cell arteritis, which is characterized by an inflammation of the temporal artery. Serum sCD23 levels, as measured by a radioimmunoassay, were increased in these patients, and returned to normal values within the 24 h following initiation of corticotherapy. The data suggest that the increase in sCD23 levels in giant cell arteritis results from an overproduction.
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
July 1972,
Lancet (London, England),
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
October 1976,
JAMA,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
December 1999,
Turkish journal of haematology : official journal of Turkish Society of Haematology,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
May 1995,
The Journal of dermatology,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
April 1994,
Clinical transplantation,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
January 1995,
Journal of investigational allergology & clinical immunology,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
January 1996,
Mediators of inflammation,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
July 2006,
The Journal of rheumatology,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
January 1998,
Clinical and experimental rheumatology,
P Roblot, and
F Morel, and
E Lelièvre, and
M H Biais-Sauvètre, and
D de Groote, and
J L Preud'homme, and
J C Lecron
June 1997,
Blood,
