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We have studied the influence of serological matching for ten HLA-DR antigens on the occurrence of acute cellular rejection in heart transplantation by correlating the findings in routine endomyocardial biopsies taken during the first posttransplant year with the results of HLA typing of all recipients of a first cardiac graft and their donors during 1983-1994 at our center. We found that recipients of HLA-DR matched hearts had a lower frequency of acute cellular rejection, especially so for the moderate/severe rejection grades. Also, rejection appeared earlier in the DR-mismatched combinations. Whether the mismatch was for one or two DR antigens did not make a significant difference, neither could we demonstrate any influence of HLA-A or -B mismatches. The survival of DR-matched cardiac grafts tended to be higher at 1 year than DR-mismatched grafts, but the difference did not reach statistical significance.
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
December 2003,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
February 1992,
Transplantation proceedings,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
October 1996,
Transplantation proceedings,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
December 1992,
Transplantation proceedings,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
January 1997,
Transplantation proceedings,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
November 1995,
Lancet (London, England),
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
November 2020,
Transplant international : official journal of the European Society for Organ Transplantation,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
February 1981,
The New England journal of medicine,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
September 1994,
Transplantation,
T Leivestad, and
A Foerster, and
S Simonsen, and
A Bratlie, and
E Thorsby, and
O Geiran
May 2019,
Journal of cardiac failure,
