Quantitative PET measurements of regional myocardial blood flow: observations in humans with ischemic heart disease. 1997

H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

This review focuses on several related issues concerning positron emission tomography measurements of regional myocardial blood flow using 13-N-ammonia in humans. The effect of partial volume correction on estimates of K1, the model parameter describing myocardial blood flow, is considered. In addition a new method for computing K1 images of myocardial flow distribution is briefly described and compared to a standard method. Potential differences between K1 and equilibrium levels of 13-N-ammonia in the myocardium for estimation of myocardial blood flow are discussed also. The issue of heterogeneity of myocardial blood flow and flow reserve in normal volunteers is considered from the clinical point of view in terms of evaluation of patients with ischemic heart disease. Finally, the use of absolute measurement of adenosine-stimulated myocardial blood flow to assess physiological significance of coronary artery stenoses is addressed.

UI MeSH Term Description Entries
D007091 Image Processing, Computer-Assisted A technique of inputting two-dimensional or three-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer. Biomedical Image Processing,Computer-Assisted Image Processing,Digital Image Processing,Image Analysis, Computer-Assisted,Image Reconstruction,Medical Image Processing,Analysis, Computer-Assisted Image,Computer-Assisted Image Analysis,Computer Assisted Image Analysis,Computer Assisted Image Processing,Computer-Assisted Image Analyses,Image Analyses, Computer-Assisted,Image Analysis, Computer Assisted,Image Processing, Biomedical,Image Processing, Computer Assisted,Image Processing, Digital,Image Processing, Medical,Image Processings, Medical,Image Reconstructions,Medical Image Processings,Processing, Biomedical Image,Processing, Digital Image,Processing, Medical Image,Processings, Digital Image,Processings, Medical Image,Reconstruction, Image,Reconstructions, Image
D008297 Male Males
D001783 Blood Flow Velocity A value equal to the total volume flow divided by the cross-sectional area of the vascular bed. Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D005260 Female Females
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000241 Adenosine A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. Adenocard,Adenoscan
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013552 Swine Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA). Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog

Related Publications

H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
January 1978, Advances in cardiology,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
November 2005, Coronary artery disease,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
April 1980, Kokyu to junkan. Respiration & circulation,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
October 1991, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
October 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
May 1999, Coronary artery disease,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
May 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
July 1988, Kaku igaku. The Japanese journal of nuclear medicine,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
December 2022, Current cardiology reports,
H Gewirtz, and H A Skopicki, and S A Abraham, and H Castano, and R E Dinsmore, and N M Alpert, and A J Fischman
January 1982, Terapevticheskii arkhiv,
Copied contents to your clipboard!