Biomaterial Database

[Adaptation to weightlessness and stress]. 1996

A I Grigor'ev, and A S Kaplanskiĭ, and G N Durnova

The literature on the problem of stress-inducing effect of weightlessness is reviewed. On the basis of scrupulous analysis of the data accumulated in the rat flight experiments aboard the Cosmos biosatellites and the US Space Life Sciences Laboratory (SLS-2) it is concluded that although the ever-acting factor of space mission, microgravity does not cause any intensive chronic stress to animals. Nonetheless, it contributes to the development of deconditioning of a number of vitally important systems and the body as a whole. On return to Earth, the usual terrestrial loads due to the gravity effects are perceived by the deconditioned animals as extraordinary and they respond by severe gravitational stress.

UI	MeSH Term	Description	Entries
D000222	Adaptation, Physiological	The non-genetic biological changes of an organism in response to challenges in its ENVIRONMENT.	Adaptation, Physiologic,Adaptations, Physiologic,Adaptations, Physiological,Adaptive Plasticity,Phenotypic Plasticity,Physiological Adaptation,Physiologic Adaptation,Physiologic Adaptations,Physiological Adaptations,Plasticity, Adaptive,Plasticity, Phenotypic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013312	Stress, Physiological	The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.	Biotic Stress,Metabolic Stress,Physiological Stress,Abiotic Stress,Abiotic Stress Reaction,Abiotic Stress Response,Biological Stress,Metabolic Stress Response,Physiological Stress Reaction,Physiological Stress Reactivity,Physiological Stress Response,Abiotic Stress Reactions,Abiotic Stress Responses,Abiotic Stresses,Biological Stresses,Biotic Stresses,Metabolic Stress Responses,Metabolic Stresses,Physiological Stress Reactions,Physiological Stress Responses,Physiological Stresses,Reaction, Abiotic Stress,Reactions, Abiotic Stress,Response, Abiotic Stress,Response, Metabolic Stress,Stress Reaction, Physiological,Stress Response, Metabolic,Stress Response, Physiological,Stress, Abiotic,Stress, Biological,Stress, Biotic,Stress, Metabolic
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014893	Weightlessness	Condition in which no acceleration, whether due to gravity or any other force, can be detected by an observer within a system. It also means the absence of weight or the absence of the force of gravity acting on a body. Microgravity, gravitational force between 0 and 10 -6 g, is included here. (From NASA Thesaurus, 1988)	Microgravity,Zero Gravity,Gravity, Zero
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D018531	Spacecraft	Devices, manned and unmanned, which are designed to be placed into an orbit about the Earth or into a trajectory to another celestial body. (NASA Thesaurus, 1988)	Biosatellites,Launch Vehicle,Satellites, Artificial,Satellites, Man-Made,Space Capsule,Space Craft,Space Probe,Space Ship,Space Shuttle,Space Vehicles,Spaceship,Artificial Satellite,Artificial Satellites,Biosatellite,Capsule, Space,Capsules, Space,Launch Vehicles,Man-Made Satellite,Man-Made Satellites,Probe, Space,Probes, Space,Satellite, Artificial,Satellite, Man-Made,Satellites, Man Made,Shuttle, Space,Shuttles, Space,Space Capsules,Space Probes,Space Ships,Space Shuttles,Space Vehicle,Spacecrafts,Spaceships,Vehicle, Launch,Vehicles, Launch