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A computer program is described for the rapid calculation of least squares solutions for data fitted to different functions normally used in reassociation and hybridization kinetic measurements. The equations for the fraction not reacted as a function of Cot follow: First order, exp(-kCot); second order, (1+kCot)-1; variable order, (1+kCot)-n; approximate fraction of DNA sequence remaining single stranded, (1+kCot)-.44; and a function describing the pairing of tracer when the rate constant for the tracer (k) is distinct from the driver rate constant (kd): (formula: see text). Several components may be used for most of these functional forms. The standard deviations of the individual parameters at the solutions are calculated.
W R Pearson, and
E H Davidson, and
R J Britten
July 1996,
Molecular pharmacology,
W R Pearson, and
E H Davidson, and
R J Britten
October 1985,
Talanta,
W R Pearson, and
E H Davidson, and
R J Britten
June 2016,
Biometrika,
W R Pearson, and
E H Davidson, and
R J Britten
December 1976,
Computer programs in biomedicine,
W R Pearson, and
E H Davidson, and
R J Britten
May 2022,
ACS omega,
W R Pearson, and
E H Davidson, and
R J Britten
June 2012,
IEEE transactions on pattern analysis and machine intelligence,
W R Pearson, and
E H Davidson, and
R J Britten
January 2014,
BMC proceedings,
W R Pearson, and
E H Davidson, and
R J Britten
April 2009,
The journal of physical chemistry. B,
W R Pearson, and
E H Davidson, and
R J Britten
January 2016,
NeuroImage,
W R Pearson, and
E H Davidson, and
R J Britten
January 2004,
NeuroImage,
