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Tumor endoprosthesis first have been used for replacement of pathologic lesions of the proximal and distal femur or humerus. Since the development of segmental defect prosthesis and modular tumor endoprosthesis it is possible to replace neoplastic lesions of long bones with diaphyseal parts. Review of our clinic experience involving 46 cases of prosthetic replacement and only one case with a second procedure showed that this is a more viable concept than open reduction and internal fixation with methylmethacrylate supplementation.
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