Biomaterial Database

Effect of suture knot location on tensile strength after flexor tendon repair. 1996

D L Pruitt, and M Aoki, and P R Manske

Department of Orthopedic Surgery, Washington University Medical School, St. Louis, MO, USA.

This study investigated the effect of increased suture material within the flexor tendon repair site on tensile strength in a canine model after in vivo healing. Four-strand modified Savage suture repairs with the knots located either inside or outside the repair site were performed in dogs. The tendons were placed on a passive-motion protocol after surgery and were biomechanically tested at 1, 3, and 6 weeks of in vivo healing. The knots-outside technique initially was 1.14 kg stronger on load-to-failure testing. After 6 weeks of healing, the knots-inside tendons had equal tensile strength (3.91 +/- 0.50 kg [inside] vs 4.16 +/- 0.66 kg [outside]). Relative tensile strength compared to initial strength showed an increase of 20% for the knots-outside technique and an increase of 67% for the knots-inside technique after 6 weeks. Suture material within the repair site did not have any deleterious effects on tensile strength and may stimulate tendon healing.

UI	MeSH Term	Description	Entries
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013536	Suture Techniques	Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).	Suture Technics,Suture Technic,Suture Technique,Technic, Suture,Technics, Suture,Technique, Suture,Techniques, Suture
D013537	Sutures	Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)	Staples, Surgical,Surgical Staples,Staple, Surgical,Surgical Staple,Suture
D013710	Tendons	Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.	Endotenon,Epotenon,Tendons, Para-Articular,Tendons, Paraarticular,Endotenons,Epotenons,Para-Articular Tendon,Para-Articular Tendons,Paraarticular Tendon,Paraarticular Tendons,Tendon,Tendon, Para-Articular,Tendon, Paraarticular,Tendons, Para Articular
D013718	Tensile Strength	The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)	Strength, Tensile,Strengths, Tensile,Tensile Strengths
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In