-transparent.png){kind=logo}
Sensitive high-performance liquid chromatographic determination of nifedipine in dog plasma using an automated sample preparation system with laboratory robot. 1996
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
Technical University of Budapest, Institute for General and Analytical Chemistry, Hungary.
Nifedipine, a calcium-channel blocking drug was analysed in dog plasma after oral dosing with two different formulations. Sample preparation was automated with a laboratory robot. Quantitative determination of the drug was performed on a reversed-phase HPLC system with electrochemical detection (ED) using an internal standard. Validation of the analytical method showed that the system is well suited for pharmacokinetic studies on dogs. The assay was linear in the range 1-50 ng/ml. Inter-day and intra-day variability were between 6.43-18.15% C.V. and 1.57-5.53% C.V., respectively.
Related Publications
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
June 1999,
Journal of chromatography. B, Biomedical sciences and applications,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
September 1984,
Journal of chromatography,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
August 1993,
Journal of chromatography,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
December 2002,
Journal of biochemical and biophysical methods,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
March 1986,
Journal of chromatography,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
January 1985,
Therapeutic drug monitoring,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
January 1991,
Biomedical chromatography : BMC,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
July 1993,
Journal of chromatography,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
December 1986,
Journal of chromatography,
V Horváth, and
A Hrabéczy-Páll, and
Z Niegreisz, and
E Kocsi, and
G Horvai, and
L Gödörházy, and
A Tolokán, and
I Klebovich, and
K Balogh-Nemes
April 1990,
Journal of chromatography,
