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We studied the effect of two different preservation solutions on mean corpuscular volume (MCV), red cell deformability and flow in narrow tubes in red blood cell concentrates. Blood from 10 healthy blood donors was processed in parallel in SAG-M (S-RBC) as well as in PAGGS-M (P-RBC) in identical aliquots. Samples were studied at days 0, 7, 14, 28 and 42 of storage. MCV was determined using a Du Pont cell counter. Whole cell deformability was determined in a Myrenne Rheodyn. Viscosity reduction in narrow tubes was determined by means of capillary viscosimetry. P-RBC showed a constant MCV over the entire storage period. In contrast, MCV of S-RBC increased and MCHC decreased during storage. P-RBC showed similar deformability and viscosity reduction during storage, whereas deformability decreased and viscosity reduction became less pronounced for S-RBC. Our study shows superior rheological properties of P-RBC. Thus, PAGGS-M may provide better hemoglobin flux and oxygen transport to tissues than SAG-M.
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 1994,
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 2014,
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001),
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 1996,
Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 1988,
Beitrage zur Infusionstherapie = Contributions to infusion therapy,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 1987,
Beitrage zu Infusionstherapie und klinische Ernahrung,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
March 2001,
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
May 2002,
Vox sanguinis,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 2000,
Vojnosanitetski pregled,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
January 2015,
American journal of veterinary research,
E P Zilow, and
G Zilow, and
P Ruef, and
O Linderkamp
February 1997,
The Indian journal of medical research,
