Experience had with percutaneous puncture treatment under echographic control in 122 patients presenting kidney cysts is shared. The indications and contraindications for treatment, puncture technique applied and drugs used for cyst epithelium sclerosis are discussed, followed by a description of an original method of cyst cavity draining. In all patients with cyst drainage duely performed the outcome of treatment is successful. Good therapeutic results upon using sclerosing substances are attained in 88.7 per cent, while in cysts not subjected to medication-in 64.3 per cent, or else the total of positive outcomes amounts to 81.8 per cent. After puncture, it is advised to insert a drain into the cystic cavity, and invariably administer sclerosing substances. The readily performed technique of puncture, lack of serious complications, short hospitalization and prompt recovery of the ability for work are unquestionable advantages of the method proposed. In case of cyst recurrence it is possible to perform secondary puncture.