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Forty-three cholangio-cholecystographies were carried out with iotroxamide. A the same time, the behavior of various serum enzymes was controlled. Iotroxamide satisfactorily demonstrated the biliary tract for the diagnosis in 37 of our patients (86.5%). Only an inadequate or incomplete evaluation was possible for 6 of our patients (13.5%). Due to the pharmacokinetic characteristics of iotroximide, the time-density ratio is very favorable. As a result, the contrast radiograph of the biliary tract including the gallbladder was available for evaluation as early as 30 minutes after the infusion and almost always within 60 minutes. Minor subjective side effects were observed in only 4 cases. With the exception of 2 cases with obstructed bile flow, the serum-enzyme level was not significantly altered after administration of the contrast medium.
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