[Serum and urinary concentrations of magnesium in patients with chronic heart failure]. 1996

V Spisák
Interné oddelenie A, NsP Zilina.

Patients with chronic heart failure suffer more frequently, due to cumulation of factors leading to impaired magnesium (Mg) metabolism, from disorders of its concentration in serum and urine. Hypomagnesaemia has a marked (statistically significant) negative impact on the one-the two-year survival of patients. The author examined 57 patients with chronic heart failure. He did not detect hypomagnesaemia in any of them (Mg levels below 0.7 mmol/l). In two instances he found reduced urinary levels of Mg (less than 1 mmol/24 hours). Surprising is the more frequent occurrence of hypermagnesaemia (Mg above 1.0 mmol/l) which has also an adverse (statistically significant) prognostic effect on the one- and two-year survival of these patients. In the discussion the author deals with the effect of individual factors and drugs on Mg concentrations in serum and urine.

UI MeSH Term Description Entries
D008274 Magnesium A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
D008297 Male Males
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D005260 Female Females
D006333 Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. Cardiac Failure,Heart Decompensation,Congestive Heart Failure,Heart Failure, Congestive,Heart Failure, Left-Sided,Heart Failure, Right-Sided,Left-Sided Heart Failure,Myocardial Failure,Right-Sided Heart Failure,Decompensation, Heart,Heart Failure, Left Sided,Heart Failure, Right Sided,Left Sided Heart Failure,Right Sided Heart Failure
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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