Laser Doppler perfusion imaging of proximal interphalangeal joints in patients with rheumatoid arthritis. 1996

W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
Institute of Biomedical & Life Sciences, University of Glasgow, U.K.

OBJECTIVE A non-invasive imaging technique (laser Doppler perfusion imaging-LDI) based on measurement of backscattered Doppler-broadened near infra-red laser radiation was used to provide two-dimensional images of perfusion over the proximal interphalangeal (PIP) joints of a group of normal subjects compared to a group of patients with rheumatoid arthritis (RA). RESULTS Some PIP joints of the RA group showed areas of increased perfusion whereas normal subjects showed much less variation in perfusion between joints. These hyperaemic areas arose from the underlying joint, as scans taken with a less penetrating red laser did not show such areas. CONCLUSIONS Apart from its obvious dermatological uses, LDI could be employed to image hyperaemia associated with a variety of inflammatory conditions affecting subcutaneous structures.

UI MeSH Term Description Entries
D007091 Image Processing, Computer-Assisted A technique of inputting two-dimensional or three-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer. Biomedical Image Processing,Computer-Assisted Image Processing,Digital Image Processing,Image Analysis, Computer-Assisted,Image Reconstruction,Medical Image Processing,Analysis, Computer-Assisted Image,Computer-Assisted Image Analysis,Computer Assisted Image Analysis,Computer Assisted Image Processing,Computer-Assisted Image Analyses,Image Analyses, Computer-Assisted,Image Analysis, Computer Assisted,Image Processing, Biomedical,Image Processing, Computer Assisted,Image Processing, Digital,Image Processing, Medical,Image Processings, Medical,Image Reconstructions,Medical Image Processings,Processing, Biomedical Image,Processing, Digital Image,Processing, Medical Image,Processings, Digital Image,Processings, Medical Image,Reconstruction, Image,Reconstructions, Image
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001783 Blood Flow Velocity A value equal to the total volume flow divided by the cross-sectional area of the vascular bed. Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D005260 Female Females
D005384 Finger Joint The articulation between the head of one phalanx and the base of the one distal to it, in each finger. Interphalangeal Joint of Hand,Interphalangeal Joint of Finger,Finger Interphalangeal Joint,Finger Interphalangeal Joints,Finger Joints,Hand Interphalangeal Joint,Hand Interphalangeal Joints,Joint, Finger,Joints, Finger
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001172 Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Rheumatoid Arthritis
D017078 Laser-Doppler Flowmetry A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates. Doppler-Laser Flowmetry,Flowmetry, Laser-Doppler,Laser-Doppler Velocimetry,Velocimetry, Laser-Doppler,Doppler Laser Flowmetry,Flowmetry, Doppler-Laser,Flowmetry, Laser Doppler,Laser Doppler Flowmetry,Laser Doppler Velocimetry,Velocimetry, Laser Doppler

Related Publications

W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
January 2003, Microvascular research,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
September 1997, Clinical orthopaedics and related research,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
October 1978, Annals of the rheumatic diseases,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
January 1966, The Medical journal of Australia,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
September 1976, The Journal of bone and joint surgery. American volume,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
January 2016, American journal of orthopedics (Belle Mead, N.J.),
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
September 1971, The Hand,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
January 1974, Scandinavian journal of rheumatology,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
January 2022, Orthopedics,
W R Ferrell, and R D Sturrock, and A K Mallik, and N C Abbot, and J C Lockhart, and W D Edmondson
September 1969, Annals of the rheumatic diseases,
Copied contents to your clipboard!