BIOMAT Database Logo BIOMAT Database Logo

Testosterone-producing benign cystic teratoma with virilism. A case report. 1996

M W Tomlinson, and A A Alaverdian, and V Alaverdian
Department of Obstetrics and Gynecology, Grace Hospital/Wayne State University, Detroit, Michigan 48325, USA.

BACKGROUND Mature cystic teratomas are common tumors in reproductive-age women. Biologic activity in a small percentage of these neoplasms is well recognized. Thyroid hormone is the most commonly secreted substance. METHODS A 25-year-old woman presented with a large abdominal mass and virilism. Preoperative evaluation revealed elevated creatinine and testosterone levels and anemia. Computed tomography (CT) showed fat-fluid levels and multiple calcifications within the mass and obstruction of the right kidney. At surgery a 30-cm left ovarian mass was removed. Left ovarian vein testosterone levels were markedly elevated. Pathology reported a mature cystic teratoma. Postoperatively the testosterone levels returned to normal. CONCLUSIONS In rare instances androgen production and virilization may occur with mature cystic teratoma.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D007674 Kidney Diseases Pathological processes of the KIDNEY or its component tissues. Disease, Kidney,Diseases, Kidney,Kidney Disease
D003560 Cysts Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues. Cyst
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013724 Teratoma A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642) Dysembryoma,Teratoid Tumor,Teratoma, Cystic,Teratoma, Mature,Teratoma, Benign,Teratoma, Immature,Teratoma, Malignant,Benign Teratoma,Benign Teratomas,Dysembryomas,Immature Teratoma,Immature Teratomas,Malignant Teratoma,Malignant Teratomas,Teratoid Tumors,Teratomas,Teratomas, Benign,Teratomas, Immature,Teratomas, Malignant,Tumor, Teratoid,Tumors, Teratoid
D013739 Testosterone A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL. 17-beta-Hydroxy-4-Androsten-3-one,17-beta-Hydroxy-8 alpha-4-Androsten-3-one,8-Isotestosterone,AndroGel,Androderm,Andropatch,Androtop,Histerone,Sterotate,Sustanon,Testim,Testoderm,Testolin,Testopel,Testosterone Sulfate,17 beta Hydroxy 4 Androsten 3 one,17 beta Hydroxy 8 alpha 4 Androsten 3 one,8 Isotestosterone
D014057 Tomography, X-Ray Computed Tomography using x-ray transmission and a computer algorithm to reconstruct the image. CAT Scan, X-Ray,CT Scan, X-Ray,Cine-CT,Computerized Tomography, X-Ray,Electron Beam Computed Tomography,Tomodensitometry,Tomography, Transmission Computed,X-Ray Tomography, Computed,CAT Scan, X Ray,CT X Ray,Computed Tomography, X-Ray,Computed X Ray Tomography,Computerized Tomography, X Ray,Electron Beam Tomography,Tomography, X Ray Computed,Tomography, X-Ray Computer Assisted,Tomography, X-Ray Computerized,Tomography, X-Ray Computerized Axial,Tomography, Xray Computed,X Ray Computerized Tomography,X Ray Tomography, Computed,X-Ray Computer Assisted Tomography,X-Ray Computerized Axial Tomography,Beam Tomography, Electron,CAT Scans, X-Ray,CT Scan, X Ray,CT Scans, X-Ray,CT X Rays,Cine CT,Computed Tomography, Transmission,Computed Tomography, X Ray,Computed Tomography, Xray,Computed X-Ray Tomography,Scan, X-Ray CAT,Scan, X-Ray CT,Scans, X-Ray CAT,Scans, X-Ray CT,Tomographies, Computed X-Ray,Tomography, Computed X-Ray,Tomography, Electron Beam,Tomography, X Ray Computer Assisted,Tomography, X Ray Computerized,Tomography, X Ray Computerized Axial,Transmission Computed Tomography,X Ray Computer Assisted Tomography,X Ray Computerized Axial Tomography,X Ray, CT,X Rays, CT,X-Ray CAT Scan,X-Ray CAT Scans,X-Ray CT Scan,X-Ray CT Scans,X-Ray Computed Tomography,X-Ray Computerized Tomography,Xray Computed Tomography
D014770 Virilism Development of male secondary SEX CHARACTERISTICS in the FEMALE. It is due to the effects of androgenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs. Androgenization,Virilization

Related Publications

M W Tomlinson, and A A Alaverdian, and V Alaverdian
[Benign retroperitoneal cystic teratoma with postoperative chylous ascites--a case report].
September 1988, Hinyokika kiyo. Acta urologica Japonica,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Spontaneous rupture of a benign cystic teratoma. A case report.
April 1987, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Benign cystic teratoma of the parotid gland: a case report.
January 2009, Acta cytologica,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Benign cystic teratoma (dermoid) of the testis. A case report.
April 1985, Indian journal of pathology & microbiology,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Benign cystic teratoma of the mesosigmoid – Report of a case.
January 2016, Srpski arhiv za celokupno lekarstvo,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Salmonellosis of benign cystic teratoma of ovary (a case report).
April 1987, Indian journal of pathology & microbiology,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report.
February 2008, The Journal of reproductive medicine,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Malignant neural elements in a benign cystic teratoma. A case report.
March 1971, Obstetrics and gynecology,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
[Malignant degeneration of benign cystic teratoma of the ovary with synchronous mediastinal teratoma. A case report].
April 2009, La Revue de medecine interne,
M W Tomlinson, and A A Alaverdian, and V Alaverdian
Gonadotropin-producing benign cystic teratoma simulating a ruptured ectopic pregnancy.
March 1994, Journal of the National Medical Association,
Copied contents to your clipboard!