Binaural interaction (BI) components in brain-stem auditory evoked potential (BAEP) and their changes with stimulus intensity and repetition rate were examined in human adult. Seven BI components were identified, which occurred between the latency range of 5 and 11 ms and coincided consistently with the latency range of BAEP waves IV-VII. Waves DV and DVII, occurring at the downslopes of BAEP waves V and VII, respectively, were the two most prominent and reproducible BI components. Wave DVII existed consistently at high, moderate and, in most cases, low stimulus intensities, suggesting that this component is neurogenic although acoustic cross-talk may account for a part of its waveform at high stimulus intensities. The latencies of all BI components increased as a function of decreasing stimulus intensity, while the interpeak intervals, especially DV-DVII, were essentially constant at different intensity levels. The amplitudes of BI components decreased slightly with decreasing intensity. As click repetition rate increased, BI wave latencies and interpeak intervals increased slightly and amplitudes decreased slightly. When repetition rate increased to above 20/s, BI components became poorly differentiated. Lower repetition rates, e.g. 10/s, are therefore preferred for routine derivation of the BI. The changes in the latency and amplitude of BI components with stimulus intensity and repetition rate were associated or concomitant with those of the corresponding BAEP components in monaural and binaural potentials. In view of the concomitant relationship between BI and BAEP latency, we designate BI components in association with the corresponding BAEP components.