Exertional collapse and sudden death associated with sickle cell trait. 1996

K K Kerle, and K D Nishimura
Martin Army Community Hospital, Fort Benning, GA 31905, USA.

The most serious complication of sickle cell trait (SCT) is sudden death during exertion. SCT often remains unrecognized in the 2.5 million African Americans affected. Exertional collapse and sudden death associated with SCT is characterized by rhabdomyolysis, heat stroke, and cardiac arrhythmia. There is a 40-fold increased risk of sudden death in affected soldiers during military basic training and there are many cases reported in athletes during preseason training. There have been no cases reported in soldiers beyond basic training. In the case presented, a soldier with 3 years of military service succumbed to SCT-associated sudden death during physical fitness testing.

UI MeSH Term Description Entries
D008297 Male Males
D008889 Military Personnel Persons including soldiers involved with the armed forces. Air Force Personnel,Armed Forces Personnel,Army Personnel,Coast Guard,Marines,Navy Personnel,Sailors,Soldiers,Submariners,Military,Force Personnel, Air,Personnel, Air Force,Personnel, Armed Forces,Personnel, Army,Personnel, Military,Personnel, Navy,Sailor,Soldier,Submariner
D009326 Naval Medicine The practice of medicine concerned with conditions affecting the health of individuals associated with the marine environment. Nautical Medicine,Medicine, Nautical,Medicine, Naval
D003645 Death, Sudden The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions. Sudden Death
D005082 Physical Exertion Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included. Physical Effort,Effort, Physical,Efforts, Physical,Exertion, Physical,Exertions, Physical,Physical Efforts,Physical Exertions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012805 Sickle Cell Trait The condition of being heterozygous for hemoglobin S. Cell Trait, Sickle,Cell Traits, Sickle,Sickle Cell Traits,Trait, Sickle Cell,Traits, Sickle Cell
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.

Related Publications

K K Kerle, and K D Nishimura
February 1997, American family physician,
K K Kerle, and K D Nishimura
April 2012, British journal of sports medicine,
K K Kerle, and K D Nishimura
March 1997, Military medicine,
K K Kerle, and K D Nishimura
May 1996, Military medicine,
K K Kerle, and K D Nishimura
November 2003, Pediatric annals,
K K Kerle, and K D Nishimura
November 1970, The New England journal of medicine,
K K Kerle, and K D Nishimura
May 2018, Sports medicine - open,
K K Kerle, and K D Nishimura
December 1994, Sports medicine (Auckland, N.Z.),
K K Kerle, and K D Nishimura
October 2012, The American journal of cardiology,
Copied contents to your clipboard!