The nature of autoantigens targeted in autoimmune endocrine diseases. 1996

Y H Song, and Y Li, and N K Maclaren
Dept of Pathology and Laboratory Medicine, University of Florida College of Medicine, Gainesville 32610, USA.

Autoimmune endocrine diseases result from autoimmune processes involving autoreactive T cells and/or autoantibodies. Considerable progress has been made in elucidating the self- (auto-) antigens involved in these processes. These include tissue-specific membrane receptors, enzymes and secreted hormones. As discussed here by Yao-Hua Song and colleagues, diagnostic and therapeutic applications should now result from these discoveries.

UI MeSH Term Description Entries
D004700 Endocrine System Diseases Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES. Endocrine Diseases,Diseases of Endocrine System,Disease, Endocrine,Disease, Endocrine System,Diseases, Endocrine,Diseases, Endocrine System,Endocrine Disease,Endocrine System Disease,System Disease, Endocrine,System Diseases, Endocrine
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001323 Autoantibodies Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them. Autoantibody
D001324 Autoantigens Endogenous tissue constituents with the ability to interact with AUTOANTIBODIES and cause an immune response. Autoantigen,Autologous Antigen,Autologous Antigens,Self-Antigen,Self-Antigens,Antigen, Autologous,Antigens, Autologous,Self Antigen,Self Antigens
D001327 Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. Autoimmune Disease,Disease, Autoimmune,Diseases, Autoimmune

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